{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:35:25Z","timestamp":1787495725635,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2009,2,3]],"date-time":"2009-02-03T00:00:00Z","timestamp":1233619200000},"content-version":"vor","delay-in-days":4143,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1997,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    : Aortic valve disease is an important and frequent clinical problem with a mortality rate as high as 50\u201380% in a 5\u2010year natural history of patients with severe aortic valve disease. Biological or mechanical prosthesis implantation is the only way to improve prognosis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Hypothesis<\/jats:italic>\n                    : The aim of our study was to assess the clinical outcome of aortic valve replacement according to the underlying valve pathology and the type of replacement device, that is, aortic homografts versus mechanical prostheses.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods<\/jats:italic>\n                    : The study group consisted of 143 patients with a mean follow\u2010up period of 4.1 \u00b1 2.7 years. All patients had annual clinical and Doppler echocardiographic evaluation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    : Total 8\u2010year mortality was 4.9% (7\/143) including early mortality of 1.4%. Eight\u2010year survival probability was not significantly higher in the homograft than in the mechanical prosthesis recipients. No differences were found among subgroups with aortic stenosis, insufficiency, and combined disease. Overall early and late complication rate (13.3 and 24.8%, respectively) was similar in homograft and mechanical valve recipients. The most common late complications were ventricular arrhythmia (10%) (Lown class I\u2013III), pre\u2010dominantly in the homograft recipients (17.7 vs. 3.7%), and heart failure (9.2%), more frequent in mechanical valve recipients (14.8 vs. 1.6%). Thromboembolic events occurred in 6.3%, infective endocarditis in 4.2% (more common in mechanical valve recipients), serious bleeding in 3.7% (only in mechanical valve recipients). There was no significant difference in early and late complication rate among subgroups (aortic stenosis, insufficiency, and combined disease). Of the patients studied, 91.6% improved in functional status after surgery, with significantly better outcome in homograft recipients. The type of preexisting valve disease did not influence clinical improvement.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusion<\/jats:italic>\n                    : Early and late mortality as well as estimated probability of survival and hemodynamic improvement at 8\u2010year follow\u2010up after aortic valve replacement are independent of the type of implanted valve. Complication rate does not depend upon the type of preexisting valve pathology, but severe late complications are more common after mechanical valve implantation than after homograft implantation.\n                  <\/jats:p>","DOI":"10.1002\/clc.4960201010","type":"journal-article","created":{"date-parts":[[2009,2,3]],"date-time":"2009-02-03T20:01:28Z","timestamp":1233691288000},"page":"843-848","source":"Crossref","is-referenced-by-count":11,"title":["Early and long\u2010term outcome of aortic valve replacement with homograft versus mechanical prosthesis\u20148\u2010year follow\u2010up study"],"prefix":"10.1002","volume":"20","author":[{"given":"Tomasz","family":"Waszyrowski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaros\u0142AW D.","family":"Kasprzak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Krzemi","family":"\u0143ska\u2010Paku\u0142a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"Dziatkowiak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janusz","family":"ZasLonka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,2,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.35.1.41"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(75)90005-3"},{"key":"e_1_2_1_4_2","first-page":"129","volume-title":"Early stenosis and calcification of glutaraldehyde\u2010preserved porcine xenografts in children Herzchirurgie","author":"Hellberg K","year":"1982"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S0022-5223(19)38542-3","article-title":"Long\u2010term comparative analysis of the Bjork\u2010Shiley and Hancock valves implanted in 1975","volume":"90","author":"Martinell J","year":"1985","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0022-5223(19)36795-9","article-title":"The pericardial valve in the aortic position ten years later","volume":"101","author":"Gonzalez\u2010Lavin L","year":"1991","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0022-5223(19)35075-5","article-title":"Aortic valve replacement for aortic infective endocarditis in 108 patients. 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Proceedings of the ESC Working Group on Valvular Heart Disease Non\u2010Invasive Assessment of Patients with Valvular Heart Disease (abstr) p.21. Basel 1992"},{"key":"e_1_2_1_14_2","first-page":"I\u2010182","article-title":"Patient status 10 or more years after \u201cfresh\u201d homograft replacement of the aortic valve","volume":"70","author":"Penta A","year":"1984","journal-title":"Circulation"},{"key":"e_1_2_1_15_2","first-page":"127","volume-title":"Tissue Heart Valves","author":"Ross DN","year":"1979"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0022-5223(19)35929-X","article-title":"Can the results of contemporary aortic valve replacement be improved?","volume":"92","author":"Christakis GT","year":"1986","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_1_17_2","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0022-5223(19)38673-8","article-title":"A 5 1\/2 year experience with the St. Jude Medical cardiac valve prosthesis. 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A comparative analysis of implantations during 1980\u20131986 for aortic stenosis","volume":"11","author":"Lund O","year":"1990","journal-title":"Eur Heart J"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198306000-00011"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960201010","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960201010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T07:34:58Z","timestamp":1698478498000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960201010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,10]]},"references-count":26,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1997,10]]}},"alternative-id":["10.1002\/clc.4960201010"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960201010","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,10]]}}}