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We describe two young men who developed life\u2010threatening aneurysm or dissection of the ascending aorta; one had a normally functioning BAV and the other was 10 years after valve replacement. The pathology of this condition is very similar to that found in the Marfan syndrome. We recommend echocardiographic surveillance of the ascending aorta at regular intervals, and consideration of beta\u2010adrenergic blockade among patients with significant dilation.<\/jats:p>","DOI":"10.1002\/clc.4960210615","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T01:34:36Z","timestamp":1233711276000},"page":"439-443","source":"Crossref","is-referenced-by-count":29,"title":["Ascending aortic aneurysm and dissection in young adults with bicuspid aortic valve: Implications for echocardiographic surveillance"],"prefix":"10.1002","volume":"21","author":[{"given":"John M.","family":"Burks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard W.","family":"Illes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward C.","family":"Keating","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem J.","family":"Lubbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,2,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(84)90418-1"},{"key":"e_1_2_1_3_2","first-page":"1669","volume-title":"In Heart Disease","author":"Pyeritz R","year":"1997"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(81)90666-9"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(70)90761-7"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90659-8"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(77)80186-0"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(28)90386-5"},{"key":"e_1_2_1_9_2","first-page":"1","article-title":"Dissecting aneurysms of the aorta in persons under forty years of age","volume":"55","author":"Gore I","year":"1953","journal-title":"Arch Pathol"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)91327-6"},{"key":"e_1_2_1_11_2","first-page":"1554","volume-title":"Heart Disease","author":"Isselbacher E","year":"1997"},{"key":"e_1_2_1_12_2","volume-title":"Heart Disease","author":"Braunwald E","year":"1997"},{"key":"e_1_2_1_13_2","volume-title":"Echocardiography","author":"Feigenbaum H","year":"1994"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(95)90267-8"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.48.1.195"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.57.5.1022"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(10)80188-3"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)91211-1"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.10.1935"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90479-7"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001573-199609000-00009"},{"key":"e_1_2_1_22_2","first-page":"669","article-title":"Progressive thoracic aortic dilation after aortic valve replacement","volume":"142","author":"Nancarrow P","year":"1984","journal-title":"Am J Radiol"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960210615","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960210615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T17:07:57Z","timestamp":1698512877000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960210615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,6]]}},"alternative-id":["10.1002\/clc.4960210615"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960210615","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,6]]}}}