{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:37:43Z","timestamp":1790264263468,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"S4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":5540,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Cardiol"],"published-print":{"date-parts":[[2000,7]]},"DOI":"10.1002\/clc.4960230703","type":"journal-article","created":{"date-parts":[[2009,7,16]],"date-time":"2009-07-16T06:53:39Z","timestamp":1247727219000},"page":"IV-4-IV-8","source":"Crossref","is-referenced-by-count":25,"special_numbering":"supplement S4","title":["Overview of the relationship between ischemia and congestive heart failure"],"prefix":"10.1002","volume":"23","author":[{"given":"Willem J.","family":"Remme","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"10.1002\/clc.4960230703-BIB1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1056\/NEJM199209033271003","article-title":"Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions","volume":"327","author":"The SOLVD Investigators","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1002\/clc.4960230703-BIB2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1056\/NEJM199108013250501","article-title":"Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure","volume":"325","author":"The SOLVD Investigators","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1002\/clc.4960230703-BIB3","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1161\/01.CIR.90.4.1765","article-title":"A randomized trial of p-blockade in heart failure. The Cardiac Insufficiency Bisoprolol Study (CIBIS)","volume":"90","author":"CIBIS Investigators and Committees","year":"1994","journal-title":"Circulation"},{"key":"10.1002\/clc.4960230703-BIB4","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1053\/euhj.1998.1481","article-title":"Contemporary management of patients with left ventricular systolic dysfunction. Results from the Study of Patients Intolerant of Converting Enzyme Inhibitors (SPICE) Registry","volume":"20","author":"Bart","year":"1999","journal-title":"Eur Heart J"},{"key":"10.1002\/clc.4960230703-BIB5","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.0954-6820.1988.tb15788.x","article-title":"Early heart failure in the population. The study of men born in 1913","volume":"223","author":"Eriksson","year":"1988","journal-title":"Acta Med Scand"},{"key":"10.1002\/clc.4960230703-BIB6","first-page":"287","article-title":"Prevalence of heart failure in three general practices in north west London","volume":"42","author":"Parameshwar","year":"1992","journal-title":"Br J Gen Pract"},{"key":"10.1002\/clc.4960230703-BIB7","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1093\/oxfordjournals.eurheartj.a060220","article-title":"Incidence of heart failure in eastern Finland: A population-based surveillance study","volume":"13","author":"Remes","year":"1992","journal-title":"Eur Heart J"},{"key":"10.1002\/clc.4960230703-BIB8","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S0735-1097(98)00634-2","article-title":"Incidence, clinical and etiologic features, and outcomes of advanced chronic heart failure: The EPICAL study","volume":"33","author":"Zannad","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"10.1002\/clc.4960230703-BIB9","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/0140-6736(92)92889-N","article-title":"Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions","volume":"340","author":"Yusuf","year":"1992","journal-title":"Lancet"},{"key":"10.1002\/clc.4960230703-BIB10","doi-asserted-by":"crossref","first-page":"3294","DOI":"10.1161\/01.CIR.96.10.3294","article-title":"Cardiovascular death and left ventricular remodeling two years after myocardial infarction: Baseline predictors and impact of long-term use of captopril: Information from the Survival and Ventricular Enlargement (SAVE) trial","volume":"96","author":"St. John Sutton","year":"1997","journal-title":"Circulation"},{"key":"10.1002\/clc.4960230703-BIB11","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM199511163332001","article-title":"Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia","volume":"333","author":"Shepherd","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1002\/clc.4960230703-BIB12","first-page":"1383","article-title":"Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)","volume":"344","author":"Scandinavian Simvastatin Survival Study Group","year":"1994","journal-title":"Lancet"},{"key":"10.1002\/clc.4960230703-BIB13","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1001\/jama.279.20.1615","article-title":"Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels. Results of AFCAPS\/TexCAPS","volume":"279","author":"Downs","year":"1998","journal-title":"J Am Med Assoc"},{"key":"10.1002\/clc.4960230703-BIB14","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1056\/NEJM199610033351401","article-title":"The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators","volume":"335","author":"Sacks","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1002\/clc.4960230703-BIB15","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1056\/NEJM199907083410202","article-title":"Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease","volume":"341","author":"Pitt","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1002\/clc.4960230703-BIB16","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/0735-1097(93)90173-X","article-title":"Abnormal systolic blood pressure response during exercise recovery in patients with angina pectoris","volume":"22","author":"Hashimoto","year":"1993","journal-title":"J Am Coll Cardiol"},{"key":"10.1002\/clc.4960230703-BIB17","doi-asserted-by":"crossref","first-page":"1A","DOI":"10.1016\/S0002-9149(98)00850-9","article-title":"Consensus recommendations for the management of chronic heart failure","volume":"83","year":"1999","unstructured":"Packer M, Cohn JN, Eds., on behalf of the Steering Committee and Membership of the Advisory Council to Improve Outcomes Nationwide in Heart Failure: Consensus recommendations for the management of chronic heart failure. Am J Cardiol 1999; 83 (suppl): 1A-38A","journal-title":"Am J Cardiol"},{"key":"10.1002\/clc.4960230703-BIB18","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/oxfordjournals.eurheartj.a015339","article-title":"The treatment of heart failure","volume":"18","author":"Task Force of the Working Group on Heart Failure of the European Society of Cardiology","year":"1997","journal-title":"Eur Heart J"},{"key":"10.1002\/clc.4960230703-BIB19","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1161\/01.CIR.100.10.1056","article-title":"Comparison of candesartan, enalapril, and their combination in congestive heart failure: Randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study","volume":"100","author":"McKelvie","year":"1999","journal-title":"Circulation"},{"key":"10.1002\/clc.4960230703-BIB20","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0140-6736(98)11181-9","article-title":"The Cardiac Insufficiency Bisoprolol Study (CIBIS II): A randomised trial","volume":"353","author":"CIBIS II Investigators and Committees","year":"1999","journal-title":"Lancet"},{"key":"10.1002\/clc.4960230703-BIB21","doi-asserted-by":"crossref","first-page":"3A","DOI":"10.1016\/0002-9149(93)90238-8","article-title":"Aldosterone and antialdosterone therapy in congestive heart failure","volume":"71","author":"Weber","year":"1993","journal-title":"Am J Cardiol"},{"key":"10.1002\/clc.4960230703-BIB22","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/S0002-9149(99)80353-1","article-title":"Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease","volume":"76","author":"Barr","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1002\/clc.4960230703-BIB23","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1161\/01.HYP.31.1.451","article-title":"Mineralcorticoid blockade reduces vascular injury in stroke-prone hypertensive rats","volume":"31","author":"Rocha","year":"1998","journal-title":"Hypertension"},{"key":"10.1002\/clc.4960230703-BIB24","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","article-title":"The effect of spironolactone on morbidity and mortality in patients with severe heart failure","volume":"341","author":"Pitt","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1002\/clc.4960230703-BIB25","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1001\/jama.1995.03520420066040","article-title":"Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure","volume":"273","author":"Garg","year":"1995","journal-title":"J Am Med Assoc"},{"key":"10.1002\/clc.4960230703-BIB26","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0140-6736(95)90865-X","article-title":"ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction","volume":"345","author":"The Fourth International Study of Infarct Survival (ISIS-4) Collaborative Group","year":"1995","journal-title":"Lancet"},{"key":"10.1002\/clc.4960230703-BIB27","first-page":"1115","article-title":"GISSI-3: Effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction","volume":"343","author":"Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico","year":"1994","journal-title":"Lancet"},{"key":"10.1002\/clc.4960230703-BIB28","first-page":"821","article-title":"Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure","volume":"342","author":"The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators","year":"1993","journal-title":"Lancet"},{"key":"10.1002\/clc.4960230703-BIB29","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1056\/NEJM199209033271001","article-title":"Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial","volume":"327","author":"Pfeffer","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1002\/clc.4960230703-BIB30","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1056\/NEJM199512213332503","article-title":"A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction","volume":"333","author":"K\u00f8ber","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1002\/clc.4960230703-BIB31","first-page":"6","article-title":"Angiotensin-converting as a multimechanistic factor in CAD","volume":"7","author":"Dzau","year":"1995","journal-title":"J Myocard Ischemia"},{"key":"10.1002\/clc.4960230703-BIB32","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/BF00877749","article-title":"Reduction of ischemic events with angiotensin-converting enzyme inhibitors: Lessons and controversy emerging from recent clinical trials","volume":"9","author":"Young","year":"1995","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1002\/clc.4960230703-BIB33","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/0002-9149(84)90634-9","article-title":"Regression of left ventricular hypertrophy from systemic hypertension by enalapril","volume":"53","author":"Nakashima","year":"1984","journal-title":"Am J Cardiol"},{"key":"10.1002\/clc.4960230703-BIB34","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.1111\/j.1440-1681.1996.tb03038.x","article-title":"Angiotensin-converting enzyme inhibitors and atherosclerosis: Relevance of animal models to human disease","volume":"23","author":"Fennessy","year":"1996","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1002\/clc.4960230703-BIB35","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1161\/01.HYP.25.4.474","article-title":"Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension","volume":"25","author":"Thybo","year":"1995","journal-title":"Hypertension"},{"key":"10.1002\/clc.4960230703-BIB36","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1161\/01.RES.53.5.557","article-title":"Role of endothelium in responses of vascular smooth muscle","volume":"53","author":"Furchgott","year":"1983","journal-title":"Circ Res"},{"key":"10.1002\/clc.4960230703-BIB37","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0021-9150(93)90201-5","article-title":"Ramipril prevents impaired endothelium-dependent relaxation in arteries from rabbits fed an atherogenic diet","volume":"100","author":"Finta","year":"1993","journal-title":"Atherosclerosis"},{"key":"10.1002\/clc.4960230703-BIB38","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1161\/01.CIR.94.3.258","article-title":"Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study","volume":"94","author":"Mancini","year":"1996","journal-title":"Circulation"},{"key":"10.1002\/clc.4960230703-BIB39","doi-asserted-by":"crossref","first-page":"327A","DOI":"10.1016\/S0735-1097(97)85139-X","article-title":"A comparative study of four antihypertensive agents on endothelial function in patients with coronary disease","volume":"31","author":"Anderson","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1002\/clc.4960230703-BIB40","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1097\/00004872-199111000-00012","article-title":"Inhibition of angiotensin-converting enzyme by ramipril in serum and tissue of man","volume":"9","author":"Erman","year":"1991","journal-title":"J Hypertens"},{"key":"10.1002\/clc.4960230703-BIB41","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2165\/00003495-199700545-00009","article-title":"Bradykinin-mediated cardiovascular protective actions of ACE inhibitors: A new dimension in anti-ischaemic therapy?","volume":"54","author":"Remme","year":"1997","journal-title":"Drugs"},{"key":"10.1002\/clc.4960230703-BIB42","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0002-9149(98)00863-7","article-title":"Acute anti-ischemic effects of perindoprilat in men with coronary artery disease and their relation with left ventricular function","volume":"83","author":"Bartels","year":"1999","journal-title":"Am J Cardiol"},{"key":"10.1002\/clc.4960230703-BIB43","first-page":"J2","article-title":"Mechanism of protective effects of ACE inhibition on coronary artery disease","volume":"19","author":"Dzau","year":"1998","journal-title":"Eur Heart J"},{"key":"10.1002\/clc.4960230703-BIB44","unstructured":"The Heart Outcomes Prevention Evaluation Study Investigators:"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960230703","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/clc.4960230703\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T23:09:51Z","timestamp":1625180991000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960230703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":44,"journal-issue":{"issue":"S4","published-print":{"date-parts":[[2000,7]]}},"URL":"https:\/\/doi.org\/10.1002\/clc.4960230703","relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}