{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T08:34:47Z","timestamp":1702283687224},"reference-count":8,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2009,2,3]],"date-time":"2009-02-03T00:00:00Z","timestamp":1233619200000},"content-version":"vor","delay-in-days":3077,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2000,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>: Single\u2010lead VDD pacing systems are an alternative to conventional DDD pacemakers in patients with atrioventricular (AV) block and normal sinus function.<\/jats:p><jats:p><jats:italic>Hypothesis<\/jats:italic>: The aim of this study was to assess changes of P\u2010wave amplitude occurring in dynamic conditions in two groups of patients with a single\u2010lead VDD and with a DDD pacing system, respectively.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: Twenty\u2010eight patients with second\u2010 or third\u2010degree AV block and normal sinus function were enrolled prospectively into the study. Seventeen patients were implanted with a single\u2010lead VDD pacing system and 11 with a DDD pacemaker. Patients were evaluated at 3 months (all patients) and at 6 months (26 patients) at supine and in dynamic conditions (postural changes, hyperventilation, and during exercise).<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: Mean P\u2010wave values at supine were 1.92 \u00b1 1.10 mV at 3 months and 1.76 \u00b1 1.01 mV at 6 months for VDD systems, and 4.63 \u00b1 2.18 mV at 3 months and 4.58 \u00b1 2.80 mV at 6 months for DDD pacemakers. In dynamic conditions, P\u2010wave amplitude changes compared with supine condition ranged between \u201474 and +226% in VDD, and between \u201453 and +138% in DDD; however P\u2010wave amplitudes showed no significant changes compared with baseline. Moreover, changes in atrial signal amplitudes did not occur randomly, and in both systems P\u2010wave amplitudes remained significantly correlated with supine values.<\/jats:p><jats:p><jats:italic>Conclusions<\/jats:italic>: A wide range of P\u2010wave amplitude variations occurs in different postural conditions or during exercise, both with single\u2010lead VDD and DDD pacing systems. However, with appropriate programming of atrial sensitivity based on supine values, constant atrial tracking can be maintained.<\/jats:p>","DOI":"10.1002\/clc.4960230909","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T04:17:49Z","timestamp":1233721069000},"page":"678-680","source":"Crossref","is-referenced-by-count":3,"title":["DDD and single\u2010lead VDD pacing: Evaluation of atrial signal dynamic changes"],"prefix":"10.1002","volume":"23","author":[{"given":"Giuseppe","family":"Boriani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Biffi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Branzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Bandini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pier Vittorio","family":"Moracchini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Capucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Sigliano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Mininno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,2,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a014911"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199601113340206"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1994.tb01519.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1988.tb03929.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90769-W"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1996.tb03332.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1994.tb03767.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00403-2"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960230909","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960230909","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T08:36:21Z","timestamp":1698568581000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960230909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,9]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2000,9]]}},"alternative-id":["10.1002\/clc.4960230909"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960230909","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,9]]}}}