{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T04:33:07Z","timestamp":1726201987070},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,8,7]],"date-time":"2009-08-07T00:00:00Z","timestamp":1249603200000},"content-version":"vor","delay-in-days":3109,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2001,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>: Over the last 4 years, several newer generation stents have become available, promising to change the scenery of coronary angioplasty (PTCA) with its attendant restenosis rate.<\/jats:p><jats:p><jats:italic>Hypothesis<\/jats:italic>: The aim of this study was to review prospectively the results of a single operator adopting a uniform approach with approximately 0.5 mm stent oversizing and high\u2010pressure (\u2265 12\u201016 bar) deployment and compare them with conventional PTCA in a series of 244 consecutive patients.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: The study included 203 men and 41 women, aged 59 \u00b1 11 years, who presented with stable angina and\/or positive exercise testing (n = 75), unstable angina (n = 161), or acute myocardial infarction (n = 8). Dilated vessels included the left anterior descending artery (n = 139), the right coronary artery (n = 86), the left circumflex artery (n = 47), the ramus branch (n = 4), or venous grafts (n = 2). Stents were implanted for dissection, suboptimal PTCA result, and electively. Two groups were compared: 83 patients who underwent balloon PTCA alone and 161 patients who also received stent(s).<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: The two groups had similar demographics, age (58 \u00b1 10 vs. 59 \u00b1 11 years), initial vessel stenosis (92 \u00b1 7 vs. 93 \u00b1 6%), and left ventricular ejection fraction (51 \u00b1 9 vs. 51 \u00b1 8%). Procedural success was also similar (97.6 vs. 99.4%), but as expected the residual stenosis was much lower in the stent group (\u2264 0 vs. 17%). The following stents were employed: J &amp; J (n = 1), NIR (n = 117), ACS (n = 59), AVE (n = 9), Inflow GoldFlex (n = 9), Crossflex (n = 5), Wictor (n = 1), Jostent (n = 16), R stent (n = 9), Seaquence (n = 2) and Wallstent (n = 1). Single stents were used in 118 patients, two stents in 31 patients, three in 6 patients, and four in 6 patients. There was one in\u2010hospital death at 3 days unrelated to the procedure. There were no events of subacute stent thrombosis; all patients in the stent group received combined therapy with aspirin and ticlopidine, the latter for 1 month. During 18 \u00b1 14 months, the clinical r\u00e8stenosis rate was significantly lower in the stent group (6.9%) than in the PTCA group (28.4%) (p = 0.001).<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic>: In a series of 244 consecutive patients, newer generation stents and a consistent approach of stent oversizing and high\u2010pressure stent deployment by a single operator resulted in high procedural success (99%), lack of stent thrombosis (0%), and a very low clinical restenosis rate (7%).<\/jats:p>","DOI":"10.1002\/clc.4960240205","type":"journal-article","created":{"date-parts":[[2009,8,8]],"date-time":"2009-08-08T09:18:30Z","timestamp":1249723110000},"page":"119-126","source":"Crossref","is-referenced-by-count":7,"title":["Reduced incidence of clinical restenosis with newer generation stents, stent oversizing, and high\u2010pressure deployment: Single\u2010operator experience"],"prefix":"10.1002","volume":"24","author":[{"given":"Antonis 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