{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:44:52Z","timestamp":1791017092418,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2009,2,3]],"date-time":"2009-02-03T00:00:00Z","timestamp":1233619200000},"content-version":"vor","delay-in-days":2896,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2001,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    : The recurrence rate of atrial fibrillation (AF) after elective cardioversion is high.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Hypothesis<\/jats:italic>\n                    : The study aimed to identify clinical predictors for successful electrical cardioversion and maintenance of sinus rhythm after a first electrical cardioversion in patients with persistent AF without concomitant antiarrhythmic drugs of class I and III.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods<\/jats:italic>\n                    : Consecutive outpatients (n = 166) with persistent AF for &gt; 1 month, scheduled for elective cardioversion, were prospectively included in the study. A clinical investigation, echocardiographic assay, and Holter electrocardiogram (ECG) before and ECG 4 weeks after cardioversion, were performed in all patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    : The mean age of the patients was 68 years (range 45\u201383) and duration of AF was 5 (1\u201348) months. Sinus rhythm was established in 124 (75%) patients. In multivariate analysis, only duration of AF &lt; 6 months (p &lt; 0.04, odds ratio [OR] 2.2, 95% confidence interval [CI] 1.1 to 4.7) and patients weight (p &lt; 0.03, OR 2.3, 95% CI 1.1 to 4.8 for weight &lt; 80 kg) were identified as independent predictors of successful cardioversion. At 4 weeks after cardioversion, only 46 (37%) of 124 patients maintained sinus rhythm. Independent factors for maintenance of sinus rhythm, in multivariate analysis, were AF &lt; 3 months (p &lt; 0.04, OR 2.5, 95% CI 1.1 to 5.6), treatment with beta blockers (p &lt; 0.00001, OR 7.0, 95% CI 3.0 to 16.3) or verapamil\/diltiazem (p &lt; 0.04, OR 3.6, 95% CI 1.0 to 12.1), and right atrial dimension &lt; 37 mm (p &lt; 0.02, OR 5.9, 95% CI 1.4 to 25.4).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions<\/jats:italic>\n                    : In patients with persistent AF, the patient's weight and the duration of AF are independent predictors for a successful cardioversion. Short duration of AF, treatment with beta blockers or verapamil\/diltiazem, and right atrial area\/dimension are independent predictors for maintenance of sinus rhythm.\n                  <\/jats:p>","DOI":"10.1002\/clc.4960240313","type":"journal-article","created":{"date-parts":[[2009,2,3]],"date-time":"2009-02-03T18:21:15Z","timestamp":1233685275000},"page":"238-244","source":"Crossref","is-referenced-by-count":114,"title":["factors predicting success rate and recurrence of atrial fibrillation after first electrical cardioversion in patients with persistent atrial 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