{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:25:31Z","timestamp":1761128731561},"reference-count":29,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2009,2,3]],"date-time":"2009-02-03T00:00:00Z","timestamp":1233619200000},"content-version":"vor","delay-in-days":2621,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>: Early reperfusion therapy has reduced the infarct size and mortality rate in patients with acute myocardial infarction (AMI). The occurrence of bundle\u2010branch block in AMI is related to the amount of myocardial damage and the insult to the conduction system.<\/jats:p><jats:p><jats:italic>Hypothesis<\/jats:italic>: To evaluate the clinical and angiographic factors related to the occurrence of bundle\u2010branch block (BBB) in patients with primary percutaneous transluminal coronary angioplasty (PTCA), we investigated consecutive series of patients with their first Q\u2010wave AMI and successful PTCA.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: Coronary angiogram at the time of admission, electrocardiogram, and echocardiogram were evaluated in 279 patients with their first Q\u2010wave AMI and successful PTCA.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: Bundle\u2010branch block was detected in 26 patients (9%) 16 patients had transient and 10 patients had persistent block, while 16 patients had bifascicular block and 10 patients had right BBB. The patients with BBB had a significantly larger number of left ventricular asynergic segments, higher incidence of total occlusion of infarct\u2010related artery, angiographic no reflow, and pericardial rub than those without BBB. When the multivariate analysis was performed using five clinical markers of infarct severity, angiographic no reflow (F = 20.2, p &lt; 0.001) and total occlusion of infarct\u2010related artery (F = 4.2, p = 0.04) were found to be the significant variables related to BBB.<\/jats:p><jats:p><jats:italic>Conclusions<\/jats:italic>: Despite successful primary PTCA, absence of antegrade flow in the infarct\u2010related artery at the onset of AMI and\/or angiographic no reflow resulted in more severe transmural myocardial damage and, hence, the occurrence of BBB.<\/jats:p>","DOI":"10.1002\/clc.4960241204","type":"journal-article","created":{"date-parts":[[2009,2,3]],"date-time":"2009-02-03T23:31:46Z","timestamp":1233703906000},"page":"770-774","source":"Crossref","is-referenced-by-count":2,"title":["Correlates of bundle\u2010branch block in patients undergoing primary angioplasty for acute myocardial 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