{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T08:10:36Z","timestamp":1700208636733},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,12,5]],"date-time":"2006-12-05T00:00:00Z","timestamp":1165276800000},"content-version":"vor","delay-in-days":1403,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2003,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>: Predischarge stress testing provides suboptimal prediction of spontaneous hard events following uncomplicated acute myocardial infarction (AMI).<\/jats:p><jats:p><jats:italic>Hypothesis<\/jats:italic>: This study was aimed at assessing whether soft cardiac ischemic events requiring late revascularization could be predicted more accurately.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: In all, 428 patients undergoing exercise electro\u2010cardiography (ECG) and stress echocardiography (SE, 345 dobutamine and 83 dypiridamole) within 15 days of uncomplicated AMI were followed up for 425 (range 20\u20102220) days. Soft ischemic events (effort angina &gt; class II [Canadian Cardiovascular Society Classification] and unstable angina) driving late (&gt; 6 months) revascularization were regarded as endpoints.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: A total of 58 events (29 effort and 29 unstable angina with subsequent 47 coronary artery bypass grafts and 11 percutaneous transluminal coronary angioplasties) occurred: 26 in patients with positive exercise ECG and 34 in patients with positive SE. Univariate predictors of revascularizations were positive exercise ECG (p = 0.0001), peak wall motion score index (WMSI) (p = 0.0009), low workload (p = 0.0018), rest WMSI (p = 0.02) and positive SE (p = 0.02). Cox multivariate analysis selected peak WMSI, positive exercise ECG, and low workload positive exercise ECG as independent predictors of late revascularizations.<\/jats:p><jats:p><jats:italic>Conclusions<\/jats:italic>: Predischarge stress testing identifies the long\u2010term occurrence of soft ischemic events driving late revascularization after uncomplicated AMI.<\/jats:p>","DOI":"10.1002\/clc.4960260205","type":"journal-article","created":{"date-parts":[[2007,6,27]],"date-time":"2007-06-27T16:22:47Z","timestamp":1182961367000},"page":"67-70","source":"Crossref","is-referenced-by-count":2,"title":["Predischarge exercise electrocardiogram and stress echocardiography can predict long\u2010term clinically driven revascularization following acute myocardial infarction"],"prefix":"10.1002","volume":"26","author":[{"given":"Alessandro","family":"Desideri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Bigi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauro","family":"Cortigiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Rambaldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Sabbadin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianpiero","family":"Curti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leopoldo","family":"Celegon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,12,5]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90357-U"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0894-7317(89)80014-8","article-title":"Recommendations for quantitation of the left ventricle by two\u2010dimensional echocardiography","volume":"2","author":"American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two\u2010Dimensional Echocardiograms","year":"1989","journal-title":"J Am Soc Echocardiogr"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(94)90819-2"},{"key":"e_1_2_1_5_2","first-page":"416","article-title":"A chart of post\u2010acute myocardial infarct risk: Results in the first 18 months of the GISSI follow\u2010up study","volume":"28","author":"Marchioli R","year":"1998","journal-title":"G Ital Cardiol"},{"key":"e_1_2_1_6_2","first-page":"1549","article-title":"Role, timing and cost\u2010effectiveness of non\u2010invasive strategies after uncomplicated myocardial infarction","volume":"29","author":"Desideri A","year":"1999","journal-title":"G Ital Cardiol"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a015195"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00425-7"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)00927-9"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/heart.85.4.417"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01083-3"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01359-X"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.6.1402"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)00476-7"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)00484-6"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00534-1"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00182-3"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00423-4"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960260205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T07:35:57Z","timestamp":1700206557000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960260205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,2]]}},"alternative-id":["10.1002\/clc.4960260205"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960260205","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,2]]}}}