{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:02:29Z","timestamp":1792670549623,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2006,12,5]],"date-time":"2006-12-05T00:00:00Z","timestamp":1165276800000},"content-version":"vor","delay-in-days":764,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background:<\/jats:italic> The Senning operation for transposition of the great arteries (TGA) was first introduced by Senning in 1959 and was revived by Quaegebeur <jats:italic>et al.<\/jats:italic> in the late 1970s, thus becoming the intervention of choice for the correction of TGA in many centers.<\/jats:p><jats:p><jats:italic>Hypothesis:<\/jats:italic> The purpose of this study was to evaluate the long\u2010term follow\u2010up of a group of patients undergoing surgery with the Senning procedure for TGA.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> From November 1978 to November 1987, 73 consecutive patients underwent the Senning operation. The 70 survivors had an average follow\u2010up of 19 years (16\u201025 years).<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> (1) Cardiac rhythm: with time there was a progressive decrease in stable sinus rhythm (60% after 20 years) and a progressive increase of supraventricular tachyarrhythmias requiring therapy (10% after 20 years). (2) Right ventricular function: 20% of the patients had reduced ejection fraction. (3) Late mortality: in the last 12 years of follow\u2010up years there were two sudden deaths (2.8%). (4) Functional status: 80% of patients were in NYHA class I, 17% in class II, and 3% in class III.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic> Our results confirm that the patients who undergo the Senning procedure have a progressive loss of sinus rhythm, an increase in active arrhythmias, and other important adverse outcomes such as late sudden death and a decrease in right ventricular function; however, most patients (93% in our series) are alive and in good functional status.<\/jats:p>","DOI":"10.1002\/clc.4960271107","type":"journal-article","created":{"date-parts":[[2007,6,27]],"date-time":"2007-06-27T19:47:13Z","timestamp":1182973633000},"page":"611-614","source":"Crossref","is-referenced-by-count":21,"title":["Long\u2010term outcome after senning operation for transposition of the great arteries"],"prefix":"10.1002","volume":"27","author":[{"given":"A.","family":"Agnetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Carano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Cavalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Tchana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Squarcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Frigiola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,12,5]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"966","article-title":"Surgical correction of transposition of the great vessels","volume":"45","author":"Senning A","year":"1959","journal-title":"Surgery"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.32.5.517"},{"issue":"1","key":"e_1_2_1_4_2","first-page":"197","article-title":"Comparative operative results of the Senning and Mustard procedures for transposition of the great arteries","volume":"62","author":"Bender HW","year":"1980","journal-title":"Circulation"},{"key":"e_1_2_1_5_2","first-page":"1145","article-title":"Improved right ventricular function after intraatrial repair of transposition of the great arteries","volume":"72","author":"Graham TP","year":"1985","journal-title":"Circulation"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(89)90272-5"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)35693-4"},{"key":"e_1_2_1_8_2","first-page":"128","volume-title":"Electrocardiographic Study in Normal Infant and Children","author":"Ziegler RF","year":"1951"},{"key":"e_1_2_1_9_2","first-page":"1442","volume-title":"Comprehensive Electrocardiography, 3","author":"Macfarlane PW","year":"1989"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1017\/S1047951100000123","article-title":"The Senning operation for complete transposition: Mean\u2010term physiologic, electrophysiologic and functional results","volume":"1","author":"Menil WH","year":"1991","journal-title":"Cardiol Young"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198709000-00003"},{"issue":"4","key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0022-5223(19)35210-9","article-title":"Arrhythmia and late mortality after Mustard and Senning operation for transposition of the great arteries: An eight\u2010year prospective study","volume":"96","author":"Deanfield JE","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951100000147"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(94)90854-0"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(99)70329-6"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00309-X"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(99)70328-4"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(90)90155-X"},{"key":"e_1_2_1_19_2","first-page":"667","volume-title":"Pediatric Arrhythmias. 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