{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T15:16:05Z","timestamp":1773155765767,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2006,12,5]],"date-time":"2006-12-05T00:00:00Z","timestamp":1165276800000},"content-version":"vor","delay-in-days":522,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>: Patients suffering from chronic isolated aortic regurgitation have a less favorable outcome than patients with aortic stenosis. According to international recommendations, these patients should undergo surgery as soon as left ventricular function begins to deteriorate, that is, surgery is not to be postponed until clinical symptoms become relevant.<\/jats:p><jats:p><jats:italic>Hypothesis<\/jats:italic>: The study was undertaken to evaluate how satisfactory our timing of surgery was, as reflected by survival data.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: Survival was studied retrospectively in a consecutive series of patients undergoing surgery for chronic isolated aortic regurgitation during a 10\u2010year period in our institution. Results were compared with data from the literature. By excluding patients with aortic aneurysms and acute endocarditis, we formed a homogeneous patient group of 88 subjects.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: Thirty\u2010day mortality was 1% and late mortality after a mean follow\u2010up period of 6 years was 11%. Compared with survival data from an earlier study in which the patient population was similar and resided in the same geographic area, the results in our patient group seem to be better. It is noteworthy that despite a strong effort to recommend surgery at an earlier stage of the disease than previously, 35% of the patients had moderate or severe left ventricular dysfunction pre\u2010operatively because of late referrals.<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic>: This stresses the importance of early detection and careful preoperative follow\u2010up with noninvasive methods in patients with aortic regurgitation.<\/jats:p>","DOI":"10.1002\/clc.4960280705","type":"journal-article","created":{"date-parts":[[2007,6,28]],"date-time":"2007-06-28T05:21:27Z","timestamp":1183008087000},"page":"329-332","source":"Crossref","is-referenced-by-count":4,"title":["Are patients with isolated chronic aortic regurgitation operated in time? Analysis of survival data over a decade"],"prefix":"10.1002","volume":"28","author":[{"given":"\u00c9va","family":"Tam\u00e1s","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Nylander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Olin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,12,5]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(90)90627-2"},{"issue":"1","key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/oxfordjournals.eurheartj.a059586","article-title":"Relative survival of patients after heart valve replacement","volume":"11","author":"Abdelnoor M","year":"1990","journal-title":"Eur Heart J"},{"issue":"2","key":"e_1_2_1_4_2","first-page":"89","article-title":"Risk factors of morbidity and mortality in surgically treated chronic aortic disease","volume":"36","author":"Abdelnoor M","year":"1988","journal-title":"Rev Epidemiol Sant\u00e9 Publique"},{"key":"e_1_2_1_5_2","first-page":"II\u2010100","article-title":"Valve replacement in chronic aortic regurgitation. True predictors of survival after extended follow\u2010up","volume":"98","author":"Turina J","year":"1998","journal-title":"Circulation"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.10.2472"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.10.2355"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2000.tb01141.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(99)70150-X"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8651(05)70025-4"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00205-2"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2000.106329"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00964-8"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1159\/000067723"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.4065\/74.1.14"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(93)90398-2"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960280705","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960280705","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T23:21:25Z","timestamp":1700176885000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960280705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["10.1002\/clc.4960280705"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960280705","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,7]]}}}