{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T14:39:56Z","timestamp":1771857596824,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This review article discussed the use of bridging therapy with low\u2010molecular\u2010weight heparin (LMWH) in patients who undergo noncardiac surgery (NCS) after percutaneous coronary intervention (PCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypotheses<\/jats:title><jats:p>Patients who undergo PCI are at an increased risk of thrombotic events due to their underlying cardiovascular disease. However, many of these patients may require NCS at some point in their lives, which poses a significant challenge for clinicians as they balance the risk of thrombotic events against the risk of bleeding associated with antithrombotic therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This review evaluates the current evidence on the use of bridging therapy with LMWH in patients undergoing NCS after PCI, focusing on outcomes related to the efficacy and safety of antithrombotic therapy. The article also discusses the limitations of the current evidence and highlights areas where further research is needed to optimize the management of antithrombotic therapy in this patient population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The goal of this review was to provide clinicians with a comprehensive summary of the available evidence to guide clinical decision\u2010making and improve patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.70008","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T05:20:57Z","timestamp":1726118457000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bridging With Low\u2010Molecular\u2010Weight Heparin Versus Antiplatelet Therapy in Patients Undergoing Noncardiac Surgery After Percutaneous Coronary Intervention: A Comprehensive Review"],"prefix":"10.1002","volume":"47","author":[{"given":"Syed Javaid","family":"Iqbal","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Research Cardiovascular Analytics Group Islamabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zulfiqar Qutrio","family":"Baloch","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Ascension Borgess Hospital  Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jahanzeb","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Research Cardiovascular Analytics Group Islamabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikeeta","family":"Bhimani","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Research Cardiovascular Analytics Group Islamabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4968-3909","authenticated-orcid":false,"given":"Amin","family":"Mehmoodi","sequence":"additional","affiliation":[{"name":"Department of Medicine Ibn e Seena Hospital Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Ascension Borgess Hospital  Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.729432"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2014.02.027"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH14-12-1057"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e328340e690"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH14-05-0436"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH15-04-0305"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25507"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1998.3.1.121"},{"key":"e_1_2_8_10_1","volume-title":"StatPearls","author":"Iftikhar S. 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