{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T05:39:49Z","timestamp":1775885989417,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Myocardial infarction without significant stenosis or occlusion of the coronary arteries carries a high risk of recurrent major adverse cardiovascular events and poor prognosis. This study aimed to investigate the association between body mass index and outcomes in patients with a suspected myocardial infarction with nonobstructive coronary artery disease (MINOCA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients were recruited at Bergmannsheil University Hospital from January 2010 to April 2021. The primary outcomes were in\u2010hospital and long\u2010term mortality. Secondary outcomes consisted of adverse events during hospitalization and during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 373 patients were included in the study, with a mean follow\u2010up time of 6.2 years. The patients were divided into different BMI groups: &lt;\u200925\u2009kg\/m\u00b2 (<jats:italic>n<\/jats:italic>\u2009=\u2009121), 25\u221230\u2009kg\/m\u00b2 (<jats:italic>n<\/jats:italic>\u2009=\u2009140), and &gt;\u200930\u2009kg\/m\u00b2 (<jats:italic>n<\/jats:italic>\u2009=\u2009112). In\u2010hospital mortality was 1.7% versus 2.1% versus 4.5% (<jats:italic>p<\/jats:italic>\u2009=\u20090.368). However, long\u2010term mortality tended to be higher in the &lt;\u200925\u2009kg\/m\u00b2 group compared to the 25\u221230 and &gt;\u200930\u2009kg\/m\u00b2 groups (log\u2010rank <jats:italic>p<\/jats:italic>\u2009=\u20090.067). Subgroup analysis using Kaplan\u2212Meier analysis showed a higher rate of cardiac cause of death in the &lt;\u200925\u2009kg\/m\u00b2 group compared to the 25\u221230 and &gt;\u200930\u2009kg\/m\u00b2 groups: 5.7% versus 1.1% versus 0.0% (log\u2010rank <jats:italic>p<\/jats:italic>\u2009=\u20090.042). No significant differences were observed in other adverse events between the different BMI groups during hospitalization and long\u2010term follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with a BMI\u2009&lt;\u200925\u2009kg\/m\u00b2 who experience a suspected myocardial infarction without significant coronary artery disease may have higher all\u2010cause mortality and cardiovascular cause of death. However, further data are needed to confirm these findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.70013","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T05:25:38Z","timestamp":1726118738000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Impact of Body Mass Index on the Mortality of Myocardial Infarction Patients With Nonobstructive Coronary Arteries"],"prefix":"10.1002","volume":"47","author":[{"given":"Chaohui","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Cellular and Translational Physiology Institute of Physiology, Ruhr\u2010University Bochum Bochum Germany"},{"name":"Institut f\u00fcr Forschung und Lehre (IFL), Molecular and Experimental Cardiology Ruhr\u2010University Bochum Bochum Germany"},{"name":"HCEMM\u2010SU Cardiovascular Comorbidities Research Group, Center for Pharmacology and Drug Research &amp; Development, Department of Pharmacology and Pharmacotherapy Int\u00e9zet c\u00edme Semmelweis University Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Kacmaz","sequence":"additional","affiliation":[{"name":"Department of Cellular and Translational Physiology Institute of Physiology, Ruhr\u2010University Bochum Bochum Germany"},{"name":"Institut f\u00fcr Forschung und Lehre (IFL), Molecular and Experimental Cardiology Ruhr\u2010University Bochum Bochum Germany"},{"name":"HCEMM\u2010SU Cardiovascular Comorbidities Research Group, Center for Pharmacology and Drug Research &amp; Development, Department of Pharmacology and Pharmacotherapy Int\u00e9zet c\u00edme Semmelweis University Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Schlettert","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Bergmannsheil University Hospital, Ruhr University of Bochum Bochum Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Abumayyaleh","sequence":"additional","affiliation":[{"name":"First Department of Medicine University Medical Centre Mannheim (UMM) Mannheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Akin","sequence":"additional","affiliation":[{"name":"First Department of Medicine University Medical Centre Mannheim (UMM) Mannheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rayyan","family":"Hemetsberger","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II Division of Cardiology, Medical University of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"M\u00fcgge","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Bergmannsheil University Hospital, Ruhr University of Bochum Bochum Germany"},{"name":"Department of Cardiology and Rhythmology University Hospital St. Josef Hospital Bochum, Ruhr University Bochum Bochum Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assem","family":"Aweimer","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Bergmannsheil University Hospital, Ruhr University of Bochum Bochum Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazha","family":"Hamdani","sequence":"additional","affiliation":[{"name":"Department of Cellular and Translational Physiology Institute of Physiology, Ruhr\u2010University Bochum Bochum Germany"},{"name":"Institut f\u00fcr Forschung und Lehre (IFL), Molecular and Experimental Cardiology Ruhr\u2010University Bochum Bochum Germany"},{"name":"HCEMM\u2010SU Cardiovascular Comorbidities Research Group, Center for Pharmacology and Drug Research &amp; Development, Department of Pharmacology and Pharmacotherapy Int\u00e9zet c\u00edme Semmelweis University Budapest Hungary"},{"name":"Department of Cardiology and Rhythmology University Hospital St. Josef Hospital Bochum, Ruhr University Bochum Bochum Germany"},{"name":"Departments of Physiology Cardiovascular Research Institute Maastricht, Maastricht University Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"El\u2010Battrawy","sequence":"additional","affiliation":[{"name":"Department of Cellular and Translational Physiology Institute of Physiology, Ruhr\u2010University Bochum Bochum Germany"},{"name":"Institut f\u00fcr Forschung und Lehre (IFL), Molecular and Experimental Cardiology Ruhr\u2010University Bochum Bochum Germany"},{"name":"Department of Cardiology and Angiology Bergmannsheil University Hospital, Ruhr University of Bochum Bochum Germany"},{"name":"Department of Cardiology and Rhythmology University Hospital St. Josef Hospital Bochum, Ruhr University Bochum Bochum 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