{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:09:11Z","timestamp":1788995351344,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ventricular tachyarrhythmia (VT) occasionally occurred in patients with Takotsubo cardiomyopathy (TC). Two convex\u2010type ST elevations were significantly related to VT in coronary artery disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study assessed the correlation between VT and critical ECG patterns, as well other independent predictive factors of in\u2010hospital outcome. Fifty\u2010five consecutive patients fulfilled the diagnostic criteria of Takotsubo Italian Network (TIN) were retrospectively enrolled. The patients were classified into two groups according to their critical ECG patterns and VT occurrence. In\u2010hospital outcomes and influencing factors were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of VT was higher in the critical ECG group than in the Noncritical ECG group (43.8% vs. 2.6%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). In\u2010hospital death was more common in the critical ECG group than in the Noncritical ECG group (25.0% vs. 5.1%, <jats:italic>p<\/jats:italic>\u2009=\u20090.032). The composite end\u2010point (combined VT and in\u2010hospital death) revealed significant differences between these two groups (50.0% vs 7.7%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Multi\u2010variate analysis proved critical ECG type as one independent risk factor of VT (odds ratio [OR]\u2009=\u200961.8, <jats:italic>p<\/jats:italic>\u2009=\u20090.009) and the composite end\u2010point (OR\u2009=\u200912.4, <jats:italic>p<\/jats:italic>\u2009=\u20090.007). The prolong QRS width (\u2009\u2265\u2009105\u2009ms) was another independent factor for predicting VT (OR\u2009=\u20091.06, <jats:italic>p<\/jats:italic>\u2009=\u20090.022) and composite end\u2010point (OR\u2009=\u20091.05, <jats:italic>p<\/jats:italic>\u2009=\u20090.017).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Critical ECG types including tombstoning ST elevation and lambda\u2010wave ST elevation have strong impact on short\u2010term outcomes. Additionally, conduction disturbance with prolong QRS\u2009\u2265\u2009105\u2009ms also has independent predicting role for poor prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.70056","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T14:33:56Z","timestamp":1733754836000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Critical Convex\u2010Type ST Elevation Correlate With Ventricular Tachyarrhythmia in Takotsubo Cardiomyopathy"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6073-102X","authenticated-orcid":false,"given":"Jen\u2010Te","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Divisions of Cardiology Lo\u2010Hsu Medical Foundation Lotung Poh\u2010Ai Hospital Yilan County Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju\u2010Feng","family":"Hsiao","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Divisions of Cardiology Lo\u2010Hsu Medical Foundation Lotung Poh\u2010Ai Hospital Yilan County Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"See\u2010Khong","family":"Chin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Divisions of Cardiology Lo\u2010Hsu Medical Foundation Lotung Poh\u2010Ai Hospital Yilan County Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Cheng","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Divisions of Cardiology Lo\u2010Hsu Medical Foundation Lotung Poh\u2010Ai Hospital Yilan County Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng\u2010Huan","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Divisions of Cardiology Lo\u2010Hsu Medical Foundation Lotung Poh\u2010Ai Hospital Yilan County Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2004.01.001"},{"key":"e_1_2_10_3_1","first-page":"190","article-title":"Lambda\u2010Like Waveform: A New Risk Predictor of Impending Malignant Arrhythmias in Patients With Coronary Artery Disease","volume":"12","author":"Xuexun L.","year":"2020","journal-title":"Interventional Cardiology"},{"issue":"3","key":"e_1_2_10_4_1","first-page":"275","article-title":"'Tombstoning' of ST Segment in Acute Myocardial Infarction\u2014Effect on Clinical Course","volume":"64","author":"Kukla P.","year":"2006","journal-title":"Kardiologia Polska"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.21088\/jcms.2454.7123.4318.4"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.2174\/157340309789317869"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.12.239"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000013561"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00059-010-3339-x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960230508"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01204.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2017.08.023"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2011.11.007"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytaa076"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12581"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ams2.377"},{"issue":"331","key":"e_1_2_10_17_1","first-page":"2","article-title":"Takotsubo Cardiomyopathy With a Tombstoning St Segment Elevation: A Case Report","volume":"6","author":"Yu B.","year":"2016","journal-title":"Emergency Medicine: Open Access"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-16-0912"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.04.002"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2015.12.010"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1984.247.2.H303"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.07.062"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043046"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.83.2.469"},{"key":"e_1_2_10_25_1","unstructured":"C. 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