{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T14:35:59Z","timestamp":1771338959101,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Left ventricular assist devices (LVADs) are utilized as a therapeutic option for patients with end\u2010stage heart failure. While LVAD implantation can enhance survival rates and quality of life, the procedure has its risks, and postoperative complications are common. This review aims to investigate whether there is an association between living in a rural area and the incidence of postoperative complications or hospital readmissions following LVAD implantation, compared to urban LVAD recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A comprehensive literature review examined studies that compared postoperative outcomes between rural and urban LVAD recipients. Data on adverse events, hospitalizations, and mortality rates were extracted, focusing on the impact of geographic location on these outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The review found that rural LVAD recipients may be at a higher risk for certain complications, including gastrointestinal bleeding, ventricular arrhythmias, LVAD complications, and stroke. Rural patients also exhibited higher instances of emergency department visits and hospital readmissions. Despite these challenges, survival rates and heart transplantation outcomes at 1 year were similar between rural and urban recipients. However, rural patients exhibited a higher driveline infection rate at 1 year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings of this review suggest that rural residency may be associated with an increased risk of certain postoperative complications and hospital readmissions following LVAD implantation. These results highlight the need for healthcare strategies to address the challenges faced by rural LVAD recipients. Further research is necessary to understand the relationship between geographic location and LVAD outcomes and to develop interventions that can improve postoperative care for this vulnerable population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.70068","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T06:29:56Z","timestamp":1735799396000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Is There an Association Between Living in a Rural Area and the Incidence of Postoperative Complications or Hospital Readmissions Following Left Ventricular Assist Device (LVAD) Implantation, Compared to Urban Lvad Recipients? A Systematic Review"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1884-5632","authenticated-orcid":false,"given":"Samrat","family":"Gollapudi","sequence":"first","affiliation":[{"name":"Department of Medicine Rowan School of Osteopathic Medicine Stratford New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6253-4678","authenticated-orcid":false,"given":"Abhiram","family":"Gollapudi","sequence":"additional","affiliation":[{"name":"Department of Research Future Forwards Research Institute Piscataway New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5924-0083","authenticated-orcid":false,"given":"Sri","family":"Banala","sequence":"additional","affiliation":[{"name":"Department of Medicine Rowan School of Osteopathic Medicine Stratford New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7474-380X","authenticated-orcid":false,"given":"Sheraj","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Research Future Forwards Research Institute Piscataway New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9280-7433","authenticated-orcid":false,"given":"Kiran","family":"Tadi","sequence":"additional","affiliation":[{"name":"Department of Research Future Forwards Research Institute Piscataway New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2018.02.003"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2011.172"},{"key":"e_1_2_13_4_1","first-page":"113","article-title":"[Left Ventricular Assist Devices (LVAD): Optional Treatment Alternative to Cardiac Transplantation?]","volume":"88","author":"Wohlschlaeger J.","year":"2004","journal-title":"Verhandlungen der Deutschen Gesellschaft fur Pathologie"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-016-0671-y"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.027251"},{"key":"e_1_2_13_7_1","volume-title":"StatPearls [Internet]","author":"Vaidya Y.","year":"2024"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.11909\/j.issn.1671-5411.2015.01.007"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.100123"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2018.09.021"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(95)00990-6"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2072-1439.2015.10.64"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.case.2020.05.015"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1098348"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11936-019-0783-7"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-98109-2"},{"key":"e_1_2_13_17_1","unstructured":"Defining Rural at the U.S. Census Bureau www2.census.gov\/geo\/pdfs\/reference\/ua\/Defining_Rural.pdf."},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jrh.12335"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/nur.22052"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/JCN.0000000000000597"},{"key":"e_1_2_13_21_1","first-page":"44","article-title":"Abstract 20156: Rural\u2010Urban Comparison of VAD\u2010Related Hospitalization Risk and Survival in the 6 Months Following Device Implantation","volume":"136","author":"Alonso W.","year":"2017","journal-title":"Circulation"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2022.06.047"},{"key":"e_1_2_13_23_1","unstructured":"N.Rajagopalan A. 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