{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T05:04:28Z","timestamp":1779858268225,"version":"3.53.1"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transesophageal echocardiography (TEE) for left atrial appendage (LAA) thrombus exclusion before cardioversion faces logistical barriers including limited availability, patient intolerance, and procedural delays. We evaluated the feasibility and short\u2010term safety of a cardiac CT\u2010based alternative pathway in hospitalized patients with atrial fibrillation (AF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective single\u2010center study included 408 consecutive AF inpatients planned for cardioversion. The primary endpoint was the composite of stroke\/TIA or systemic embolism within 48\u2009h post\u2010cardioversion. Secondary endpoints included 30\u2010day thromboembolic events, acute kidney injury, and all\u2010cause mortality at 30 days and 1 year. Imaging modality selection was based on availability, clinical factors, and contraindications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 74 patients undergoing CT\u2010guided cardioversion and 206 undergoing TEE\u2010guided cardioversion, no strokes or TIAs occurred within 48\u2009h in either group (0\/74 CT vs. 0\/206 TEE,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.0). By 30 days, one TIA occurred in the CT group (1.4%) and none in the TEE group (0%), representing an absolute risk difference of +1.4% (95% CI: \u22120.8% to +7.3%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.26). Acute kidney injury occurred in 8.1% of CT patients compared with 3.9% in the TEE group (absolute risk difference +4.2%, 95% CI: \u22121.4% to +12.9%; OR 2.18, 95% CI: 0.60\u20137.45;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.21). No mortality was observed at 30 days or 1 year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this single\u2010center feasibility analysis, a CT\u2010based imaging pathway for LAA assessment prior to cardioversion was associated with no periprocedural thromboembolic events and acceptable short\u2010term safety. Prospective randomized trials are needed to define the clinical role of CT as an alternative to TEE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/clc.70323","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T12:26:50Z","timestamp":1777292810000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Safety and Feasibility of a CT\u2010Based Pathway for Left Atrial Appendage Assessment Prior to Inpatient Cardioversion: A Single\u2010Center Experience"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2458-9548","authenticated-orcid":false,"given":"Ariel","family":"Furer","sequence":"first","affiliation":[{"name":"Department of Cardiology Chaim Sheba Medical Center Ramat\u2010Gan Israel"},{"name":"Department of Military Medicine, Faculty of Medicine The Hebrew University of Jerusalem Jerusalem 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