{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T06:37:30Z","timestamp":1789799850410,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      An electrocardiographic (ECG) pattern\u2014terminal s\u2010wave in lead V\n                      <jats:sub>2<\/jats:sub>\n                      with monophasic R waves in other precordial leads\u2014may help identify a subset of left ventricular outflow tract (LVOT) idiopathic ventricular arrhythmias (IVAs) amenable to acute successful endocardial ablation. However, further clinical validation is needed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study included 93 patients with LVOT IVAs displaying the defined ECG pattern.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Acute successful endocardial ablation was achieved in 70 patients (75.3%; successful endocardial ablation group), while the remaining 23 patients (24.7%; endocardial ablation failure group) required epicardial ablation or had unsuccessful outcomes. The s\u2010wave amplitude in lead V\n                      <jats:sub>2<\/jats:sub>\n                      was significantly deeper in the successful than in the failure group (5.0\u2009\u00b1\u20092.6 vs. 2.1\u2009\u00b1\u20091.1\u2009mV,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000). In the successful group, the most common effective ablation sites were the left\/right coronary sinus (LCC\/RCC) commissure subvalvularly (52 patients, 55.9%) and anterior mitral annulus near the aorto\u2010mitral continuity (AMC) (18 patients, 19.4%). In the failure group, success was achieved via the coronary venous system (11 patients), combined endo\u2010epicardial ablation (3 patients), percutaneous epicardial access or surgical epicardial ablation (3 patients); one procedure failed due to proximity to the left main coronary artery, and 5 patients declined epicardial ablation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Among patients with this ECG phenotype, approximately 75% can be successfully ablated endocardially at the LCC\/RCC commissure subvalvularly or the anterior mitral annulus near the AMC. Greater terminal S\u2010wave amplitude in lead V\n                      <jats:sub>2<\/jats:sub>\n                      is associated with an increased likelihood of acute endocardial ablation success.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/clc.70332","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T12:57:18Z","timestamp":1776949038000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Terminal S\u2010Wave Amplitude in Lead V\n                    <sub>2<\/sub>\n                    With Monophasic R Waves in Other Precordial Leads: A Novel ECG Marker for Predicting Acute Successful Endocardial Ablation of a Subtype of Left Ventricular Outflow Tract Idiopathic Ventricular Arrhythmias"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7777-574X","authenticated-orcid":false,"given":"Chengye","family":"Di","sequence":"first","affiliation":[{"name":"First Department of Cardiology TEDA International Cardiovascular Hospital Tianjin China"},{"name":"College of Clinical Cardiology Tianjin Medical University Tianjin China"},{"name":"Cardiovascular Institute Tianjin University Tianjin China"},{"name":"Chengde Medical University, Chengde Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6921-9970","authenticated-orcid":false,"given":"Longyu","family":"Li","sequence":"additional","affiliation":[{"name":"First Department of Cardiology TEDA International Cardiovascular Hospital Tianjin China"},{"name":"College of Clinical Cardiology Tianjin Medical University Tianjin China"},{"name":"Cardiovascular Institute Tianjin University Tianjin China"},{"name":"Chengde Medical University, Chengde Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3436-2056","authenticated-orcid":false,"given":"Qun","family":"Wang","sequence":"additional","affiliation":[{"name":"First Department of Cardiology TEDA International Cardiovascular Hospital Tianjin China"},{"name":"College of Clinical Cardiology Tianjin Medical University Tianjin China"},{"name":"Cardiovascular Institute Tianjin University Tianjin China"},{"name":"Chengde Medical University, Chengde Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0446-7324","authenticated-orcid":false,"given":"Yanxi","family":"Wu","sequence":"additional","affiliation":[{"name":"First Department of Cardiology TEDA International Cardiovascular Hospital Tianjin China"},{"name":"College of Clinical Cardiology Tianjin Medical University Tianjin China"},{"name":"Cardiovascular Institute Tianjin University Tianjin 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