{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T10:38:06Z","timestamp":1792751886048,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006983","name":"iRhythm Technologies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006983","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Comparative effectiveness data across ambulatory cardiac monitoring (ACM) modalities are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To confirm and extend comparative findings across ACM modalities and vendors in commercially insured and Medicare Advantage beneficiaries without prior arrhythmia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective study using Optum Research Database. Adults\u2009\u2265\u200918 years with first ACM use between January 1, 2017 and June 30, 2022 were categorized as long\u2010term continuous monitors (LTCM), Holter, external ambulatory event monitors (AEM), or mobile cardiac telemetry (MCT). Outcomes were arrhythmia diagnosis (90 days), repeat monitoring (180 days), cardiovascular events, hospitalization, emergency department [ED] visits, and costs (365 days). Inverse probability of treatment weighting used a specific LTCM (iRhythm Technologies, San Francisco, CA) as reference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 352,782 patients (mean age 62.0\u2009\u00b1\u200917.1 years; 61% female), 25% received LTCM, 37% Holter, 20% AEM, and 18% MCT. Among LTCM users, 58% received iRhythm LTCM. Compared with this LTCM, Holter, MCT, and other LTCM had lower odds of arrhythmia diagnosis (IPTW\u2010weighted ORs 0.50\u22120.95;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01); AEM did not differ. Repeat monitoring was higher for other LTCM, AEM, and Holter (IPTW\u2010weighted ORs 1.99\u22122.77;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001); MCT did not differ. All other modalities had higher IPTW\u2010weighted odds of cardiovascular events (ORs 1.10\u22121.66;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), hospitalization (ORs 1.12\u22122.04;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), ED visits (ORs 1.09\u22122.08;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and costs (IPTW\u2010weighted cost ratios 1.03\u22121.28;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Outcomes differed across ACM modalities and vendors, confirming observations in other payer populations. A specific LTCM was associated with higher claims\u2010based arrhythmia yield and lower repeat monitoring than most alternatives, and with lower hospitalization, health care utilization, and costs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/clc.70500","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:24:48Z","timestamp":1792160688000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Clinical Outcomes Across Ambulatory Cardiac Monitoring Modalities"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8003-7254","authenticated-orcid":false,"given":"Suneet","family":"Mittal","sequence":"first","affiliation":[{"name":"Valley Health System Paramus New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8675-8186","authenticated-orcid":false,"given":"Matthew R.","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Lahey Hospital &amp; Medical Center Burlington Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Hughes","sequence":"additional","affiliation":[{"name":"Optum Eden Prairie Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin K.","family":"Buysman","sequence":"additional","affiliation":[{"name":"Optum Eden Prairie Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik M.","family":"Hendrickson","sequence":"additional","affiliation":[{"name":"iRhythm Technologies San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3244-6793","authenticated-orcid":false,"given":"Ken","family":"Boyle","sequence":"additional","affiliation":[{"name":"iRhythm Technologies San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7173-7667","authenticated-orcid":false,"given":"Brent","family":"Wright","sequence":"additional","affiliation":[{"name":"iRhythm Technologies San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey M.","family":"Ashburner","sequence":"additional","affiliation":[{"name":"iRhythm Technologies San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8025-0904","authenticated-orcid":false,"given":"Mintu P.","family":"Turakhia","sequence":"additional","affiliation":[{"name":"iRhythm Technologies San Francisco California USA"},{"name":"Stanford University Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rod S.","family":"Passman","sequence":"additional","affiliation":[{"name":"Northwestern University School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.118.006273"},{"key":"e_1_2_10_3_1","first-page":"645","article-title":"Electrophysiology and Heart Rhythm Disorders in Older Adults","volume":"13","author":"Goyal P.","year":"2016","journal-title":"Journal of geriatric cardiology: JGC"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hroo.2022.07.010"},{"key":"e_1_2_10_5_1","first-page":"e41","article-title":"2025 Correction to: 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data from the American Heart Association","volume":"151","author":"Martin S. 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