{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T12:07:47Z","timestamp":1788955667420,"version":"build-2803163510"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2021,9,19]],"date-time":"2021-09-19T00:00:00Z","timestamp":1632009600000},"content-version":"vor","delay-in-days":49,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Clinical Liver Disease"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1002\/cld.1092","type":"journal-article","created":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T04:41:59Z","timestamp":1632112919000},"page":"90-95","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Alcoholic Hepatitis"],"prefix":"10.1097","volume":"18","author":[{"given":"Amir","family":"Gougol","sequence":"first","affiliation":[{"name":"Center for Liver Diseases,University of Pittsburgh Medical Center,Pittsburgh,PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Clemente\u2010Sanchez","sequence":"additional","affiliation":[{"name":"Center for Liver Diseases,University of Pittsburgh Medical Center,Pittsburgh,PA"},{"name":"CIBERehd,Instituto de Salud Carlos III,Madrid,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josepmaria","family":"Argemi","sequence":"additional","affiliation":[{"name":"Center for Liver Diseases,University of Pittsburgh Medical Center,Pittsburgh,PA"},{"name":"University of Navarra,Pamplona,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon","family":"Bataller","sequence":"additional","affiliation":[{"name":"Center for Liver Diseases,University of Pittsburgh Medical Center,Pittsburgh,PA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,9,19]]},"reference":[{"key":"cld1092-bib-0001-20241015","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/hep.30866","article-title":"Diagnosis and treatment of alcohol\u2010associated liver diseases: 2019 Practice Guidance from the American Association for the Study of Liver Diseases","volume":"71","year":"2020","journal-title":"Hepatology"},{"key":"cld1092-bib-0002-20241015","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/apt.15376","article-title":"Systematic review with meta\u2010analysis: high mortality in patients with non\u2010severe alcoholic hepatitis","volume":"50","year":"2019","journal-title":"Aliment Pharmacol Ther"},{"key":"cld1092-bib-0003-20241015","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1001\/jamapsychiatry.2017.2161","article-title":"Prevalence of 12\u2010month alcohol use, high\u2010risk drinking, and DSM\u2010IV alcohol use disorder in the United States, 2001\u20102002 to 2012\u20102013: results from the National Epidemiologic Survey on Alcohol and Related Conditions","volume":"74","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"cld1092-bib-0004-20241015","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1056\/NEJMra0805786","article-title":"Alcoholic hepatitis","volume":"360","year":"2009","journal-title":"N Engl J Med"},{"key":"cld1092-bib-0005-20241015","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/hep.20503","article-title":"MELD accurately predicts mortality in patients with alcoholic hepatitis","volume":"41","year":"2005","journal-title":"Hepatology"},{"key":"cld1092-bib-0006-20241015","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/ajg.2016.539","article-title":"A day\u20104 Lille model predicts response to corticosteroids and mortality in severe alcoholic hepatitis","volume":"112","year":"2017","journal-title":"Am J Gastroenterol"},{"key":"cld1092-bib-0007-20241015","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/hep.27779","article-title":"Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis","volume":"62","year":"2015","journal-title":"Hepatology"},{"key":"cld1092-bib-0008-20241015","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jhep.2018.02.022","article-title":"The prognostic value of acute\u2010on\u2010chronic liver failure during the course of severe alcoholic hepatitis","volume":"69","year":"2018","journal-title":"J Hepatol"},{"key":"cld1092-bib-0009-20241015","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1056\/NEJMoa1412278","article-title":"Prednisolone or pentoxifylline for alcoholic hepatitis","volume":"372","year":"2015","journal-title":"N Engl J Med"},{"key":"cld1092-bib-0010-20241015","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1053\/j.gastro.2016.12.019","article-title":"In patients with severe alcoholic hepatitis, prednisolone increases susceptibility to infection and infection\u2010related mortality, and is associated with high circulating levels of bacterial DNA","volume":"152","year":"2017","journal-title":"Gastroenterology"},{"key":"cld1092-bib-0011-20241015","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1056\/NEJMoa1101214","article-title":"Glucocorticoids plus N\u2010acetylcysteine in severe alcoholic hepatitis","volume":"365","year":"2011","journal-title":"N Engl J Med"},{"key":"cld1092-bib-0012-20241015","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1002\/lt.20267","article-title":"Liver transplantation for alcoholic liver disease: current concepts and length of sobriety","volume":"10","year":"2004","journal-title":"Liver Transpl"},{"key":"cld1092-bib-0013-20241015","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1002\/hep.21607","article-title":"The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids","volume":"45","year":"2007","journal-title":"Hepatology"},{"key":"cld1092-bib-0014-20241015","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1056\/NEJMoa1105703","article-title":"Early liver transplantation for severe alcoholic hepatitis","volume":"365","year":"2011","journal-title":"N Engl J Med"},{"key":"cld1092-bib-0015-20241015","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1053\/j.gastro.2018.04.009","article-title":"Outcomes of early liver transplantation for patients with severe alcoholic hepatitis","volume":"155","year":"2018","journal-title":"Gastroenterology"},{"key":"cld1092-bib-0016-20241015","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1002\/hep.29240","article-title":"Main drivers of outcome differ between short term and long term in severe alcoholic hepatitis: a prospective study","volume":"66","year":"2017","journal-title":"Hepatology"},{"key":"cld1092-bib-0017-20241015","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1001\/jama.2018.12086","article-title":"Screening and behavioral counseling interventions to reduce unhealthy alcohol use in adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force","volume":"320","year":"2018","journal-title":"JAMA"},{"key":"cld1092-bib-0018-20241015","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1001\/jama.2014.3628","article-title":"Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta\u2010analysis","volume":"311","year":"2014","journal-title":"JAMA"},{"key":"cld1092-bib-0019-20241015","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1053\/j.gastro.2015.12.038","article-title":"Intensive enteral nutrition is ineffective for patients with severe alcoholic hepatitis treated with corticosteroids","volume":"150","year":"2016","journal-title":"Gastroenterology"},{"key":"cld1092-bib-0020-20241015","doi-asserted-by":"crossref","first-page":"100139","DOI":"10.1016\/j.jhepr.2020.100139","article-title":"Granulocyte colony\u2010stimulating factor for alcoholic hepatitis: a systematic review and meta\u2010analysis of randomised controlled trials","volume":"2","year":"2020","journal-title":"JHEP Rep"}],"container-title":["Clinical Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cld.1092","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cld.1092","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1002\/cld.1092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T22:04:39Z","timestamp":1729029879000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1002\/cld.1092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.1002\/cld.1092","relation":{},"ISSN":["2046-2484","2046-2484"],"issn-type":[{"value":"2046-2484","type":"print"},{"value":"2046-2484","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"2020-10-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}