{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:43:32Z","timestamp":1753868612084,"version":"3.41.2"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp; Translational All"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Rationale<\/jats:title><jats:p>It is unclear how each individual asthma symptom is associated with asthma diagnosis or control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the performance of individual asthma symptoms in the identification of patients with asthma and their association with asthma control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this cross\u2010sectional study, we assessed real\u2010world data using the MASK\u2010air<jats:sup>\u00ae<\/jats:sup> app. We compared the frequency of occurrence of five asthma symptoms (dyspnea, wheezing, chest tightness, fatigue and night symptoms, as assessed by the Control of Allergic Rhinitis and Asthma Test [CARAT] questionnaire) in patients with probable, possible or no current asthma. We calculated the sensitivity, specificity and predictive values of each symptom, and assessed the association between each symptom and asthma control (measured using the e\u2010DASTHMA score). Results were validated in a sample of patients with a physician\u2010established diagnosis of asthma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurement and Main Results<\/jats:title><jats:p>We included 951 patients (2153 CARAT assessments), with 468 having probable asthma, 166 possible asthma and 317 no evidence of asthma. Wheezing displayed the highest specificity (90.5%) and positive predictive value (90.8%). In patients with probable asthma, dyspnea and chest tightness were more strongly associated with asthma control than other symptoms. Dyspnea was the symptom with the highest sensitivity (76.1%) and the one consistently associated with the control of asthma as assessed by e\u2010DASTHMA. Consistent results were observed when assessing patients with a physician\u2010made diagnosis of asthma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Wheezing and chest tightness were the asthma symptoms with the highest specificity for asthma diagnosis, while dyspnea displayed the highest sensitivity and strongest association with asthma control.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clt2.12358","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T11:54:17Z","timestamp":1716897257000},"source":"Crossref","is-referenced-by-count":0,"title":["Relevance of individual bronchial symptoms for asthma diagnosis and control in patients with rhinitis: A MASK\u2010air study"],"prefix":"10.1002","volume":"14","author":[{"given":"Bernardo","family":"Sousa\u2010Pinto","sequence":"first","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"Faculty of Medicine CINTESIS@RISE \u2010 Health Research Network University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7111-285X","authenticated-orcid":false,"given":"Gilles","family":"Louis","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"GIGA I3 Research Group University of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1834-3055","authenticated-orcid":false,"given":"Rafael J.","family":"Vieira","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"Faculty of Medicine CINTESIS@RISE \u2010 Health Research Network University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wienczyslawa","family":"Czarlewski","sequence":"additional","affiliation":[{"name":"Medical Consulting Czarlewski  Levallois France"},{"name":"MASK\u2010air  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep M.","family":"Anto","sequence":"additional","affiliation":[{"name":"ISGlobal Barcelona Institute for Global Health  Barcelona Spain"},{"name":"Universitat Pompeu Fabra (UPF)  Barcelona Spain"},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP)  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Amaral","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"Faculty of Medicine CINTESIS@RISE \u2010 Health Research Network University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"S\u00e1\u2010Sousa","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"Faculty of Medicine CINTESIS@RISE \u2010 Health Research Network University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luisa","family":"Brussino","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences University of Torino  Torino Italy"},{"name":"Allergy and Clinical Immunology Unit Mauriziano Hospital  Torino Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Walter","family":"Canonica","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Humanitas University  Milan Italy"},{"name":"Asthma and Allergy Unit IRCCS Humanitas Research Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Chaves","family":"Loureiro","sequence":"additional","affiliation":[{"name":"Department of Pneumology Faculty of Medicine Coimbra University Hospital  Coimbra Portugal"},{"name":"Coimbra Institute for Clinical and Biomedical Research, CIBB  Coimbra Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro A.","family":"Cruz","sequence":"additional","affiliation":[{"name":"Funda\u00e7ao ProAR Federal University of Bahia and GARD\/WHO Planning Group  Salvador Bahia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilun","family":"Gemicioglu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Diseases Faculty of Medicine Istanbul University\u2010Cerrahpa\u015fa Cerrahpa\u015fa  Istanbul Turkey"},{"name":"Institute of Pulmonology and Tuberculosis Istanbul University\u2010Cerrahpa\u015fa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tari","family":"Haahtela","sequence":"additional","affiliation":[{"name":"Skin and Allergy Hospital Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Kupczyk","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital Medical University of Lodz  Lodz Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Violeta","family":"Kvedariene","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine Clinic of Chest Diseases and Allergology Faculty of Medicine Vilnius University  Vilnius Lithuania"},{"name":"Department of Pathology Institute of Biomedical Sciences Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5713-5331","authenticated-orcid":false,"given":"Desir\u00e9e E.","family":"Larenas\u2010Linnemann","sequence":"additional","affiliation":[{"name":"Center of Excellence in Asthma and Allergy M\u00e9dica Sur Clinical Foundation and Hospital  M\u00e9xico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nh\u00e2n","family":"Pham\u2010Thi","sequence":"additional","affiliation":[{"name":"Ecole Polytechnique de Palaiseau  Palaiseau France"},{"name":"IRBA (Institut de Recherche Bio\u2010M\u00e9dicale des Arm\u00e9es)  Br\u00e9tigny sur Orge France"},{"name":"Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Puggioni","sequence":"additional","affiliation":[{"name":"IRCCS Humanitas Research Center Personalized Medicine Asthma &amp; Allergy  Rozzano, Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederico S.","family":"Regateiro","sequence":"additional","affiliation":[{"name":"Allergy and Clinical Immunology Unit Centro Hospitalar e Universit\u00e1rio de Coimbra  Coimbra Portugal"},{"name":"Faculty of Medicine Center for Innovative Biomedicine and Biotechnology (CIBB) University of Coimbra  Coimbra Portugal"},{"name":"Faculty of Medicine Institute of Immunology University of Coimbra  Coimbra Portugal"},{"name":"UBIAir \u2010 Clinical &amp; Experimental Lung Centre and CICS\u2010UBI Health Sciences Research Centre University of Beira Interior  Covilh\u00e3 Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Romantowski","sequence":"additional","affiliation":[{"name":"Department of Allergology Medical University of Gda\u0144sk  Gdansk Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaquin","family":"Sastre","sequence":"additional","affiliation":[{"name":"Allergy Service Fundacion Jimenez Diaz Autonoma University of Madrid CIBERES\u2010ISCIII  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Scichilone","sequence":"additional","affiliation":[{"name":"PROMISE Department University of Palermo  Palermo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Taborda\u2010Barata","sequence":"additional","affiliation":[{"name":"UBIAir \u2010 Clinical &amp; Experimental Lung Centre and CICS\u2010UBI Health Sciences Research Centre University of Beira Interior  Covilh\u00e3 Portugal"},{"name":"Department of Immunoallergology Cova da Beira University Hospital Centre  Covilh\u00e3 Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2637-4583","authenticated-orcid":false,"given":"Maria Teresa","family":"Ventura","sequence":"additional","affiliation":[{"name":"Allergy and Clinical Immunology University of Bari Medical School  Bari Italy"},{"name":"Institute of Sciences of Food Production National Research Council (ISPA\u2010CNR)  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioana","family":"Agache","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Transylvania University Brasov  Brasov Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Bedbrook","sequence":"additional","affiliation":[{"name":"MASK\u2010air  Montpellier France"},{"name":"ARIA  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alida","family":"Benfante","sequence":"additional","affiliation":[{"name":"PROMISE Department University of Palermo  Palermo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl C.","family":"Bergmann","sequence":"additional","affiliation":[{"name":"Institute of Allergology Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Immunology and Allergology  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinthia","family":"Bosnic\u2010Anticevich","sequence":"additional","affiliation":[{"name":"Quality Use of Respiratory Medicines Group Woolcock Institute of Medical Research  Sydney New South Wales Australia"},{"name":"Macquarie Medical School Macquarie University  Macquarie Park New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Bonini","sequence":"additional","affiliation":[{"name":"Department of Public Health and Infectious Diseases Sapienza University of Rome  Rome Italy"},{"name":"National Heart and Lung Institute (NHLI) Imperial College London  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis\u2010Philippe","family":"Boulet","sequence":"additional","affiliation":[{"name":"Quebec Heart and Lung Institute Laval University  Quebec City Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy","family":"Brusselle","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Ghent University Hospital  Ghent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Buhl","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Mainz University Hospital  Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Cecchi","sequence":"additional","affiliation":[{"name":"SOS Allergology and Clinical Immunology USL Toscana Centro  Prato Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis","family":"Charpin","sequence":"additional","affiliation":[{"name":"Clinique des Bronches Allergie et Sommeil H\u00f4pital Nord  Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisio M.","family":"Costa","sequence":"additional","affiliation":[{"name":"CINTESIS@RISE Biochemistry Lab Faculty of Pharmacy and Competence Center on Active and Healthy Ageing University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Del Giacco","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology University Hospital \u201cDuilio Casula\u201d University of Cagliari  Cagliari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Jutel","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Wroc\u0142aw Medical University  Wroclaw Poland"},{"name":"ALL\u2010MED Medical Research Institute  Wroclaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludger","family":"Klimek","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery Universit\u00e4tsmedizin Mainz  Mainz Germany"},{"name":"Center for Rhinology and Allergology  Wiesbaden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Kuna","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital Medical University of Lodz  Lodz Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Laune","sequence":"additional","affiliation":[{"name":"KYomed INNOV  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika","family":"Makela","sequence":"additional","affiliation":[{"name":"Skin and Allergy Hospital Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Morais\u2010Almeida","sequence":"additional","affiliation":[{"name":"Allergy Center CUF Descobertas Hospital  Lisbon Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Nadif","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay UVSQ University Paris\u2010Sud  Villejuif France"},{"name":"Inserm Equipe d\u2019Epid\u00e9miologie Respiratoire Int\u00e9grative CESP  Villejuif France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Niedoszytko","sequence":"additional","affiliation":[{"name":"UBIAir \u2010 Clinical &amp; Experimental Lung Centre and CICS\u2010UBI Health Sciences Research Centre University of Beira Interior  Covilh\u00e3 Portugal"},{"name":"Department of Allergology Medical University of Gda\u0144sk  Gdansk Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos G.","family":"Papadopoulos","sequence":"additional","affiliation":[{"name":"Allergy Department 2nd Pediatric Clinic University of Athens  Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6924-4500","authenticated-orcid":false,"given":"Alberto","family":"Papi","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Department of Translational Medicine University of Ferrara  Ferrara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4374-9639","authenticated-orcid":false,"given":"Oliver","family":"Pfaar","sequence":"additional","affiliation":[{"name":"Section of Rhinology and Allergy Department of Otorhinolaryngology Head and Neck Surgery University Hospital Marburg Philipps\u2010Universit\u00e4t Marburg  Marburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Rivero\u2010Yeverino","sequence":"additional","affiliation":[{"name":"Servicio de Alergia e Inmunolog\u00eda cl\u00ednica Hospital Universitario de Puebla  Puebla M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Roche","sequence":"additional","affiliation":[{"name":"Inserm Equipe d\u2019Epid\u00e9miologie Respiratoire Int\u00e9grative CESP  Villejuif France"},{"name":"Pneumologie AP\u2010HP Centre Universit\u00e9 de Paris Cit\u00e9 H\u00f4pital Cochin  Paris France"},{"name":"UMR 1016 Institut Cochin  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boleslaw","family":"Samolinski","sequence":"additional","affiliation":[{"name":"Department of Prevention of Environmental Hazards Allergology and Immunology Medical University of Warsaw  Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3425-3463","authenticated-orcid":false,"given":"Mohamed H.","family":"Shamji","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute (NHLI) Imperial College London  London UK"},{"name":"NIHR Imperial Biomedical Research Centre  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aziz","family":"Sheikh","sequence":"additional","affiliation":[{"name":"Usher Institute The University of Edinburgh  Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte Suppli","family":"Ulrik","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Copenhagen University Hospital\u2010Hvidovre  Copenhagen Denmark"},{"name":"Institute of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar S.","family":"Usmani","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute (NHLI) Imperial College London  London UK"},{"name":"Institute of Clinical Medicine University of Copenhagen  Copenhagen Denmark"},{"name":"Airways Disease Section Royal Brompton Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arunas","family":"Valiulis","sequence":"additional","affiliation":[{"name":"Interdisciplinary Research Group of Human Ecology Institute of Clinical Medicine and Institute of Health Sciences Medical Faculty of Vilnius University  Vilnius Lithuania"},{"name":"European Academy of Paediatrics (EAP\/UEMS\u2010SP)  Brussel Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arzu","family":"Yorgancioglu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Diseases Faculty of Medicine Celal Bayar University  Manisa Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1466-8875","authenticated-orcid":false,"given":"Torsten","family":"Zuberbier","sequence":"additional","affiliation":[{"name":"Institute of Allergology Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Immunology and Allergology  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joao A.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"Faculty of Medicine CINTESIS@RISE \u2010 Health Research Network University of Porto  Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benoit","family":"P\u00e9tr\u00e9","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renaud","family":"Louis","sequence":"additional","affiliation":[{"name":"GIGA I3 Research Group University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"Department of Pulmonary Medicine CHU Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4061-4766","authenticated-orcid":false,"given":"Jean","family":"Bousquet","sequence":"additional","affiliation":[{"name":"MASK\u2010air  Montpellier France"},{"name":"ARIA  Montpellier France"},{"name":"Institute of Allergology Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Immunology and Allergology  Berlin Germany"},{"name":"Inserm Equipe d\u2019Epid\u00e9miologie Respiratoire Int\u00e9grative CESP  Villejuif France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"MASK\u2010air think tank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02730-2021"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201804\u20100682ci"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2021.106724"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild\u20102016\u2010311368"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd\u201020\u20102360"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/jxx.0000000000000109"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f167"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.2147\/ppa.s385857"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.4338\/aci\u20102017\u201007\u2010r\u20100116"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13601\u2010019\u20100252\u20100"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15248"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.09.012"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2022.12.005"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.4104\/pcrj.2013.00012"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398\u20109995.2009.02310.x"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/clt2.12194"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01585\u20102021"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pulmoe.2022.10.005"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13601\u2010018\u20100227\u20106"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14422"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13218"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2589\u20107500(23)00020\u20101"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.10.010"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.14325"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18031015"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2022.107098"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40945\u2010019\u20100056\u20105"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201111\u20102042st"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2010.09.013"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.11.72"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231911470"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/clt2.12054"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136\u2010022\u201003339\u20100"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/clt2.12215"}],"container-title":["Clinical and Translational Allergy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clt2.12358","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T04:23:11Z","timestamp":1723004591000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clt2.12358"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,28]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/clt2.12358"],"URL":"https:\/\/doi.org\/10.1002\/clt2.12358","archive":["Portico"],"relation":{},"ISSN":["2045-7022","2045-7022"],"issn-type":[{"type":"print","value":"2045-7022"},{"type":"electronic","value":"2045-7022"}],"subject":[],"published":{"date-parts":[[2024,5,28]]},"article-number":"e12358"}}