{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:59:35Z","timestamp":1792119575600,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp; Translational All"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Prick\u2010to\u2010prick (PTP) test with fresh food is accepted as a reliable tool for measuring sensitization to fruits and vegetables. Not all fruits and vegetables are available throughout the year. The objective of this study was to investigate whether skin prick test (SPT) performed with frozen juice of fruits and vegetables (FJFV) is a good alternative to PTP tests performed with fresh fruits and vegetables (FFV).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adult patients suspected of having a food allergy to fruits and\/or vegetables were included. A questionnaire was used to score symptoms after consumption of apple, kiwi, peach, tomato, and carrot. SPTs with FJFV, and PTP tests with FFV were performed. Intra\u2010class correlation coefficients (ICC) between the SPT and PTP test results were calculated. The sensitivity and specificity of both diagnostic tests towards food allergen specific symptoms (FASS) were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010six patients were included. FASS was positive in 75% for apple, 53% for kiwi, 44% for peach, 25% for tomato, and 22% for carrot. ICC between SPT and PTP test results were moderate for apple (0.72) and kiwi (0.71), strong for peach (0.75) and tomato (0.89), and very strong for carrot (0.94). Sensitivity was equal for the SPT and PTP tests for apple (0.93), peach (0.81), and carrot (1.00), and comparable for kiwi (0.50 resp. 0.70), and tomato (0.44 resp. 0.56). Specificity was equal for apple (0.33), peach (0.15), and carrot (0.41), and comparable for kiwi (0.29 resp. 0.21) and tomato (0.80 resp. 0.72).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Results of SPT with FJFV and PTP test with FFV are comparable. SPT with FJFV is a good alternative in the daily practice of the allergists.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clt2.12375","type":"journal-article","created":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T04:06:33Z","timestamp":1720238793000},"source":"Crossref","is-referenced-by-count":9,"title":["Comparison of skin prick test and prick\u2010to\u2010prick test with fruits and vegetables in the diagnosis of food allergy"],"prefix":"10.1002","volume":"14","author":[{"given":"Severina","family":"Terlouw","sequence":"first","affiliation":[{"name":"Department of Allergology Albert Schweitzer Hospital  Zwijndrecht The Netherlands"},{"name":"Internal Medicine Allergology &amp; Clinical Immunology Erasmus MC University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6520-1477","authenticated-orcid":false,"given":"Frank E.","family":"van Boven","sequence":"additional","affiliation":[{"name":"Internal Medicine Allergology &amp; Clinical Immunology Erasmus MC University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Borsboom\u2010van Zonneveld","sequence":"additional","affiliation":[{"name":"Department of Allergology Albert Schweitzer Hospital  Zwijndrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tineke","family":"de Graaf\u2010in \u2019t Veld","sequence":"additional","affiliation":[{"name":"Department of Allergology Albert Schweitzer Hospital  Zwijndrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Gerth van Wijk","sequence":"additional","affiliation":[{"name":"Internal Medicine Allergology &amp; Clinical Immunology Erasmus MC University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul L. 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