{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:31:01Z","timestamp":1788827461700,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004012","name":"Jane ja Aatos Erkon S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004012","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010114","name":"Yrj\u00f6 Jahnssonin S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010114","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008493","name":"V\u00e4in\u00f6 ja Laina Kiven S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008493","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp; Translational All"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim was to evaluate the predictive potential of Sinonasal Radiological (SR) and the Lund\u2010Mackay (LM) score of sinus computed tomography (CT) scans on postoperative relapses of chronic rhinosinusitis (CRS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>CRS patients (<jats:italic>n<\/jats:italic>\u00a0=\u00a0483, 12\u201380\u00a0years) underwent routine sinus CT scans. The SR score was defined by obstructed frontal recess (0\u00a0=\u00a0no, 1\u00a0=\u00a0yes) and visualization of middle and inferior turbinate (0\u00a0=\u00a0anatomy can be easily visualized, 1\u00a0=\u00a0anatomy cannot be easily visualized) on each side (a total of 0\u20136 points). Associations were analyzed by nonparametric, survival and Cox's proportional hazard models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Revision endoscopic sinus surgery (ESS) was performed in 133 (28.0%) patients on average (min\u2013max) of 3.2 (0\u201312) years after performing the sinus CT scans. Of the 408 patients who underwent the baseline ESS, high preoperative SR or LM scores significantly predicted revision ESS (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) and peroral corticosteroid courses purchased during the follow\u2010up (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.009 and <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001, respectively for SR\u2010 and LM\u2010scores). In multivariable analysis, both SR score and asthma and\/or NSAID exacerbated respiratory disease (N\u2010ERD) were significantly associated with revision ESS risk (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.035, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.007, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LM and SR and a history of asthma or N\u2010ERD predict CRS relapses, which may help in decision\u2010making.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clt2.70043","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T14:44:06Z","timestamp":1743777846000},"source":"Crossref","is-referenced-by-count":6,"title":["Radiological score, asthma and NSAID\u2010exacerbated respiratory disease predict relapsing chronic rhinosinusitis"],"prefix":"10.1002","volume":"15","author":[{"given":"Markus","family":"Lilja","sequence":"first","affiliation":[{"name":"Department of Allergology Inflammation Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Helsinki University Hospital and University of Helsinki  Helsinki Finland"},{"name":"Department of Otorhinolaryngology Hyvink\u00e4\u00e4 Hospital Hospital District of Helsinki and Uusimaa  Hyvink\u00e4\u00e4 Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anni","family":"Koskinen","sequence":"additional","affiliation":[{"name":"Department of Allergology Inflammation Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sari","family":"Hammar\u00e8n\u2010Malmi","sequence":"additional","affiliation":[{"name":"Department of Allergology Inflammation Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Laulajainen\u2010Hongisto","sequence":"additional","affiliation":[{"name":"Department of Allergology Inflammation Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jura","family":"Numminen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology &amp; Head and Neck Surgery Faculty of Medicine and Health Technology Tampere University Hospital Wellbeing Services County of Pirkanmaa Tampere University  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyri","family":"Myller","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Wellbeing Services County of P\u00e4ij\u00e4t\u2010H\u00e4me P\u00e4ij\u00e4t\u2010H\u00e4me Central Hospital  Lahti Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seija","family":"Vento","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elina","family":"Penttila","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Kuopio University Hospital Wellbeing Services County of North Savo  Kuopio Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maija","family":"Hyt\u00f6nen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Helsinki University Hospital and University of Helsinki  Helsinki 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