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Whether telomere length is associated with atopic dermatitis remains unclear. This population\u2010based case\u2010control study aimed to investigate the association between telomere length and atopic dermatitis in school\u2010age children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this cross\u2010sectional analysis, we included 1084 singleton term\u2010born children (608 males; mean age 6.4\u00a0years) from the Longitudinal Investigation of Global Health in Taiwanese Schoolchildren cohort. Telomere length was measured using quantitative real\u2010time polymerase chain reaction, log\u2010transformed and was analyzed in quartiles. The main outcome was atopic dermatitis defined as having physician\u2010diagnosed atopic dermatitis and the presence of atopic dermatitis in the last 12\u00a0months. Regression analyses were used to assess the relationship between telomere length and atopic dermatitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Telomere length was significantly inversely associated with childhood atopic dermatitis after adjusting for child's age, sex, overweight or obesity, birth season, childhood allergic diseases, environmental tobacco smoke, parental history of allergic diseases, parental educational level, and breastfeeding status (<jats:italic>p<\/jats:italic>_<jats:sub>trend<\/jats:sub>\u00a0=\u00a00.01). Specifically, when telomere length was classified into quartiles, children in the shortest (fourth) telomere length quartile had a 1.88\u2010fold higher probability of atopic dermatitis compared to those in the longest (first) quartile (95% confidence interval: 1.13\u20133.14). Stratified analyses showed that the associations were stronger in males and non\u2010breastfed children, with no significant associations observed in females or breastfed children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study provides new evidence suggesting an association between shorter telomere length and atopic dermatitis in school\u2010age children.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clt2.70066","type":"journal-article","created":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T03:05:17Z","timestamp":1748487917000},"source":"Crossref","is-referenced-by-count":3,"title":["Association between telomere length and atopic dermatitis among school\u2010age children"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2254-9598","authenticated-orcid":false,"given":"Hsin\u2010Yi","family":"Huang","sequence":"first","affiliation":[{"name":"Division of Allergy, Asthma, and Rheumatology Department of Pediatrics 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