{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:30:31Z","timestamp":1761625831883,"version":"build-2065373602"},"reference-count":9,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp; Translational All"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mobile health (mHealth) applications for asthma and allergic rhinitis (AR) may guide patients in following medication use, symptoms, and lung function supporting self\u2010management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The primary study objective was to investigate the objective effect of birch pollen on asthma and AR symptoms and medicine use in pediatric patients with varying levels of birch\u2010specific immunoglobulin E (IgE) during the 2022 birch pollen season using digital tools. The secondary objectives were to determine the effect of birch pollen on Asthma Control Test scores, and to record the subjective benefits in self\u2010management while using the application.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Altogether, 48 pediatric participants were categorized into three groups based on their birch\u2010specific IgE levels. Participants continued their existing asthma control therapy. For allergic rhinitis and conjunctivitis, antihistamines, intranasal corticosteroids (INCS) or a combination of INCS and intranasal antihistamines, and cromoglicates or local antihistamines were prescribed. The study involved daily asthma and allergic rhinitis symptom and medication reporting via the mHealth application (KAMU Health, Finland) combined with microspirometry during the birch pollen season in Helsinki, Finland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The patients preferred oral AR treatment. However, the low birch pollen levels may have contributed to moderate adherence to AR treatment. A low birch pollen load does not significantly impair lung function in young patients receiving anti\u2010asthmatic treatment regularly. The majority of patients perceived this digital approach as beneficial, irrespective of their level of birch\u2010specific sensitization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Digital tools support asthma and AR care by enabling disease monitoring, patient engagement, and provide real\u2010world insights for clinicians.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/clt2.70101","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T05:21:11Z","timestamp":1759209671000},"source":"Crossref","is-referenced-by-count":0,"title":["Digital Monitoring of Symptoms and Lung Function During Birch Pollen Season in Pediatric Patients"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1444-0173","authenticated-orcid":false,"given":"Tiina Helena","family":"Tanninen","sequence":"first","affiliation":[{"name":"Department of Allergology University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula Hannele","family":"Reiter\u00e4","sequence":"additional","affiliation":[{"name":"Biostatistics Unit Department of Public Health University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annika","family":"Saarto","sequence":"additional","affiliation":[{"name":"Biodiversity Unit University of Turku  Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janne","family":"Burman","sequence":"additional","affiliation":[{"name":"Department of Allergology University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Susanna","family":"Pelkonen","sequence":"additional","affiliation":[{"name":"Department of Allergology University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika Juhani","family":"M\u00e4kel\u00e4","sequence":"additional","affiliation":[{"name":"Department of Allergology University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2024.06.040"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2019.00301"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/falgy.2024.1451768"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2024.2336082"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13092"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.12.662"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.09.008"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25782"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12653"}],"container-title":["Clinical and Translational Allergy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clt2.70101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:23:19Z","timestamp":1761625399000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clt2.70101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,29]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/clt2.70101"],"URL":"https:\/\/doi.org\/10.1002\/clt2.70101","archive":["Portico"],"relation":{},"ISSN":["2045-7022","2045-7022"],"issn-type":[{"type":"print","value":"2045-7022"},{"type":"electronic","value":"2045-7022"}],"subject":[],"published":{"date-parts":[[2025,9,29]]},"article-number":"e70101"}}