{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:03:45Z","timestamp":1790337825895,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical &amp; Translational All"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To demonstrate an evaluation of the use of artificial intelligence (AI) in supporting tasks in evidence synthesis (particularly search for primary studies) in the allergy or respirology fields.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We queried three AI\u2010based platforms specialised on identifying scientific publications using several strategies (i.e., prompting strategies and search approaches) in November 2024 to identify primary studies related to health\u2010related case studies in the allergy or respirology field. We compared how many eligible primary studies we identified using AI\u2010based platforms versus in a systematic search in multiple electronic bibliographic databases. We also compared meta\u2010analytical results obtained with the primary studies identified by querying AI\u2010based platforms versus in the context of a systematic review. Finally, we developed a structured methodological framework and a reporting checklist for using these AI\u2010based platforms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In our main case study, a systematic review of randomised controlled trials (RCTs) informing the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines, a strategy involving searching multiple AI\u2010based platforms identified 85.7% of all full articles with DOI, but failed to identify unpublished trials registered in trial databases, resulting in an overall identification of 56.3% eligible RCTs. Meta\u2010analytical estimates were similar when considering only the primary studies identified using AI\u2010based strategies versus those identified by the systematic review. We observed a lower performance in the case study of systematic reviews of observational studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We provide an example on how it is possible to evaluate AI\u2010based platforms in the support of evidence synthesis, with a focus on the allergy and respirology fields.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/clt2.70202","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:37:33Z","timestamp":1789180653000},"source":"Crossref","is-referenced-by-count":0,"title":["Use of Artificial Intelligence\u2010Based Platforms to Support Searches in Evidence Synthesis Studies: A Study of the EAACI Methodology Committee"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1277-3401","authenticated-orcid":false,"given":"Bernardo","family":"Sousa\u2010Pinto","sequence":"first","affiliation":[{"name":"MEDCIDS \u2013 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS@RISE \u2013 Health Research Network Faculty of Medicine University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0128-903X","authenticated-orcid":false,"given":"Antonio","family":"Bognanni","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Research Center (CERC) Department of Biomedical Sciences Humanitas University  Milan Italy"},{"name":"Personalized Medicine, Asthma and Allergy IRCCS Humanitas Research Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawe\u0142","family":"Jemio\u0142o","sequence":"additional","affiliation":[{"name":"AGH University of Krakow  Krakow Poland"},{"name":"Chair of Epidemiology and Preventive Medicine Faculty of Medicine Jagiellonian University Medical College  Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1834-3055","authenticated-orcid":false,"given":"Rafael Jos\u00e9","family":"Vieira","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2013 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS@RISE \u2013 Health Research Network Faculty of Medicine University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6660-6556","authenticated-orcid":false,"given":"Thinh H.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Immunology Boston Children's Hospital Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7091-5842","authenticated-orcid":false,"given":"Zachary","family":"Munn","sequence":"additional","affiliation":[{"name":"Health Evidence Synthesis, Recommendations and Impact (HESRI) School of Public Health University of Adelaide  Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6897-814X","authenticated-orcid":false,"given":"Timothy Hugh","family":"Barker","sequence":"additional","affiliation":[{"name":"Health Evidence Synthesis, Recommendations and Impact (HESRI) School of Public Health University of Adelaide  Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9528-5595","authenticated-orcid":false,"given":"Lemma N.","family":"Bulto","sequence":"additional","affiliation":[{"name":"Health Evidence Synthesis, Recommendations and Impact (HESRI) School of Public Health University of Adelaide  Adelaide Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9728-3806","authenticated-orcid":false,"given":"Danilo","family":"di Bona","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Science University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4061-4766","authenticated-orcid":false,"given":"Jean","family":"Bousquet","sequence":"additional","affiliation":[{"name":"Institute of Allergology Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t Zu Berlin  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Allergology and Immunology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0121-6850","authenticated-orcid":false,"given":"M\u00e1rio","family":"Dinis\u2010Ribeiro","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2013 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"Precancerous Lesions and Early Cancer Management Group Research Center of IPO Porto (CI\u2010IPOP)\/CI\u2010IPOP@RISE (Health Research Group) Portuguese Institute of Oncology of Porto (IPO Porto)\/Porto Comprehensive Cancer Center (Porto.CCC)  Porto Portugal"},{"name":"Gastroenterology Department Portuguese Institute of Oncology of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o A.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2013 Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS@RISE \u2013 Health Research Network Faculty of Medicine University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4815-6894","authenticated-orcid":false,"given":"Mariette","family":"Awad","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering American University of Beirut  Beirut Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9827-2551","authenticated-orcid":false,"given":"Manuel","family":"Marques\u2010Cruz","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2013 Department of Community 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