{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T09:06:43Z","timestamp":1787994403512,"version":"build-2784847793"},"reference-count":239,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101864"],"award-info":[{"award-number":["82101864"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2025MS508"],"award-info":[{"award-number":["ZR2025MS508"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cytoskeleton"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Microtubules are critical components of the cytoskeleton that are extensively involved in various cellular and biological processes. The execution of these functions is intricately linked to post\u2010translational modifications of tubulin. Post\u2010translational modifications of tubulin include acetylation, tyrosination, de\u2010tyrosination, glutamylation, SUMOylation, and so on. These modifications are closely associated with a wide range of biological processes. Accumulating evidence indicates that aberrant microtubule modifications are implicated in various diseases, including cancer, Alzheimer's disease, neurodevelopmental disorders, cardiac atrial hypertrophy, and even infertility. Aneuploid oocytes are a common cause of infertility, spontaneous abortion, trisomy syndrome, and other congenital abnormalities. The occurrence of aneuploidy is often closely associated with defects in spindle assembly, which are influenced by a series of tubulin modifications. In this review, we aimed to summarize the factors that affect tubulin modification and explore the key mechanisms underlying aneuploidy in human oocytes, thereby providing new insights and strategies for the treatment of infertility and prevention of congenital defects in newborns.<\/jats:p>","DOI":"10.1002\/cm.70062","type":"journal-article","created":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T06:55:28Z","timestamp":1761980128000},"page":"661-677","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Post\u2010Translational Modifications of Tubulin in Oocyte Maturation and Female Infertility"],"prefix":"10.1002","volume":"83","author":[{"given":"Changying","family":"Wang","sequence":"first","affiliation":[{"name":"Institute of Immunology and Molecular Medicine, Key Laboratory of Cell and Biomedical Technology of Shandong Province, College of Basic Medicine, Jining Medical University  Jining China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runhan","family":"Guo","sequence":"additional","affiliation":[{"name":"Institute of Immunology and Molecular Medicine, Key Laboratory of Cell and Biomedical Technology of Shandong Province, College of Basic Medicine, Jining Medical University  Jining China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuenan","family":"Wang","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of the Jining Medical University  Jining China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Ji'nan Maternity and Child Care Hospital  Ji'nan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3898-057X","authenticated-orcid":false,"given":"Tao","family":"Zhong","sequence":"additional","affiliation":[{"name":"Institute of Immunology and Molecular Medicine, Key Laboratory of Cell and Biomedical Technology of Shandong Province, College of Basic Medicine, Jining Medical University  Jining China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao4165"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E15-03-0137"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09324"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan0092"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3219"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2004.04.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.11.4685"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-008-0603-8"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e12-03-0195"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2018101090"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-46379-5"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2021.11.019"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2443.2001.00413.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1975.tb02435.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2022.119241"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.259108"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa5175"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1973.tb07578.x"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1998.1839"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M207442200"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.241802"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2021108498"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M011380200"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.46902"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddaa275"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00207a014"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1227104"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2015.00132"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2022.04.020"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.65.1.227"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M308357200"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000216"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/cm.970080309"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmx010"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dew322"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-018-0283-3"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.119.315947"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13119"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddiscovery.2016.6"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2012.160"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E10-03-0203"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.10.033"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8217"},{"issue":"3","key":"e_1_2_8_45_1","first-page":"375","article-title":"Post\u2010Translational Modifications of Tubulin and the Dynamics of Microtubules in Mouse Oocytes and Zygotes","volume":"64","author":"Pennart H.","year":"1988","journal-title":"Biology of the Cell"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2013.01.029"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.4161\/cc.24901"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2006.11.008"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.15.10618"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2022.119269"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.30.18099"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0037-07.2007"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M510127200"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2007.03.017"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.026492"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1967194"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD9960485"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409626102"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1900441116"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2022.110001"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2017.12.011"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2016-103891"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201910064"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.4161\/nucl.2.6.17604"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e05-07-0621"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2021.12.003"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2022112101"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1214604"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2012.34"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2010.09.012"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.10.062"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2006.12.010"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31918"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2018.10.005"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-022-01082-9"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm243"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05867-1"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202405170"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13036"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.34.2.647"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa9529"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2022.119317"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2017.03.005"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.202697"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/417455a"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.772143"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41436-018-0415-8"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-024-05227-x"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-020-0214-3"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2017.10.044"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.31131"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-39256-0"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2021.12.004"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.43.26799"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-024-01589-8"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2962"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2024.103885"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.67925"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.12.115"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.embor.7400980"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201948290"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.464792"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.add7397"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09207"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.185983"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C110.194233"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.4573"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-animal-031412-103647"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31069-x"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1080\/09513590.2020.1725968"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1252651"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.07.091"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00323a034"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-015-2000-5"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-023-02894-0"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/18457"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.7.2367-2377.2000"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2020.126256"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2022.10.008"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1080\/15384101.2017.1329067"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-023-01000-5"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-024-05213-3"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000820"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky001"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.4.5.445"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-407699-0.00002-9"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.70193"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2024.116703"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-024-01599-0"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.102.3.1067"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.1042\/EBC20180031"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2013.03.083"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2020.08.012"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-030123-032748"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.108.095042"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.1.00793"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202101015"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrrev.2020.108320"},{"key":"e_1_2_8_139_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.202838"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2022112812"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200605019"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3284"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2007.05.002"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.1.208"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao5676"},{"key":"e_1_2_8_146_1","doi-asserted-by":"publisher","DOI":"10.1038\/30288"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(03)00038-8"},{"key":"e_1_2_8_148_1","doi-asserted-by":"crossref","unstructured":"Nottke A. C. H.\u2010M.Kim andM. P.Colai\u00e1covo.2017.\u201cWrestling With Chromosomes: The Roles of SUMO During Meiosis.\u201dSUMO Regulation of Cellular Processes: 185\u2013196. Cham Springer International Publishing.","DOI":"10.1007\/978-3-319-50044-7_11"},{"key":"e_1_2_8_149_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E14-11-1514"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2016.03.027"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.8.4.637"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddz186"},{"key":"e_1_2_8_153_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-018-0445-8"},{"key":"e_1_2_8_154_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M407950200"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.07.005"},{"key":"e_1_2_8_156_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.115.130336"},{"key":"e_1_2_8_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2017.11.2769"},{"key":"e_1_2_8_158_1","doi-asserted-by":"crossref","unstructured":"Peris L. X.Qu J.\u2010M.Soleilhac et\u00a0al.2021.\u201cImpaired \u03b1\u2010Tubulin Re\u2010Tyrosination Leads to Synaptic Dysfunction and Is a Feature of Alzheimer's Disease.\u201dBioRxiv 2021.2005. 2017.443847.","DOI":"10.1101\/2021.05.17.443847"},{"key":"e_1_2_8_159_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200512058"},{"key":"e_1_2_8_160_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200902142"},{"key":"e_1_2_8_161_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3220"},{"key":"e_1_2_8_162_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060384"},{"key":"e_1_2_8_163_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3481"},{"key":"e_1_2_8_164_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-021-16489-4"},{"key":"e_1_2_8_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2021.12.018"},{"key":"e_1_2_8_166_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.05188-11"},{"key":"e_1_2_8_167_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15496"},{"key":"e_1_2_8_168_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7992051"},{"key":"e_1_2_8_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2006.09.014"},{"key":"e_1_2_8_170_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-08-03316.2003"},{"key":"e_1_2_8_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.10.014"},{"key":"e_1_2_8_172_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2020.06.008"},{"key":"e_1_2_8_173_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M400149-MCP200"},{"key":"e_1_2_8_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(92)81061-P"},{"key":"e_1_2_8_175_1","doi-asserted-by":"publisher","DOI":"10.1111\/jmi.12841"},{"key":"e_1_2_8_176_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom13061010"},{"key":"e_1_2_8_177_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2021.12.012"},{"key":"e_1_2_8_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.06.025"},{"key":"e_1_2_8_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2020.145227"},{"key":"e_1_2_8_180_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.200231"},{"key":"e_1_2_8_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2024.03.022"},{"key":"e_1_2_8_182_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201711178"},{"key":"e_1_2_8_183_1","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2012.3"},{"key":"e_1_2_8_184_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0070-2153(06)77004-1"},{"key":"e_1_2_8_185_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abj3944"},{"key":"e_1_2_8_186_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.112.101014"},{"issue":"1","key":"e_1_2_8_187_1","first-page":"1","article-title":"Microtubule Acetylation and PERK Activation Facilitate Eribulin\u2010Induced Mitochondrial Calcium Accumulation and Cell Death","volume":"82","author":"Song S.","year":"2025","journal-title":"Cellular and Molecular Life Sciences"},{"key":"e_1_2_8_188_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.01.036"},{"key":"e_1_2_8_189_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200305080"},{"key":"e_1_2_8_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90390-K"},{"key":"e_1_2_8_191_1","doi-asserted-by":"publisher","DOI":"10.1002\/prot.24093"},{"key":"e_1_2_8_192_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.880761"},{"key":"e_1_2_8_193_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-52729-0"},{"key":"e_1_2_8_194_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2022.10.003"},{"key":"e_1_2_8_195_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2020107204"},{"key":"e_1_2_8_196_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.11.018"},{"key":"e_1_2_8_197_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.245464"},{"key":"e_1_2_8_198_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.59.2.267"},{"key":"e_1_2_8_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2021.05.009"},{"key":"e_1_2_8_200_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e14-06-1072"},{"key":"e_1_2_8_201_1","doi-asserted-by":"publisher","DOI":"10.1042\/EBC20180028"},{"key":"e_1_2_8_202_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-020-00905-0"},{"key":"e_1_2_8_203_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.01.019"},{"key":"e_1_2_8_204_1","doi-asserted-by":"publisher","DOI":"10.1038\/289650a0"},{"key":"e_1_2_8_205_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2007.04.012"},{"key":"e_1_2_8_206_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0611562104"},{"key":"e_1_2_8_207_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00527.2005"},{"key":"e_1_2_8_208_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(87)90679-6"},{"key":"e_1_2_8_209_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22073785"},{"key":"e_1_2_8_210_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.171280"},{"key":"e_1_2_8_211_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2017.165"},{"key":"e_1_2_8_212_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.229047"},{"key":"e_1_2_8_213_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202400989R"},{"key":"e_1_2_8_214_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0351379"},{"key":"e_1_2_8_215_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2115708119"},{"key":"e_1_2_8_216_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M409203200"},{"key":"e_1_2_8_217_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep41428"},{"key":"e_1_2_8_218_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abq7361"},{"key":"e_1_2_8_219_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.ado1022"},{"key":"e_1_2_8_220_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3356"},{"key":"e_1_2_8_221_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aai8764"},{"key":"e_1_2_8_222_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.09.075"},{"key":"e_1_2_8_223_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.2020-110"},{"key":"e_1_2_8_224_1","doi-asserted-by":"publisher","DOI":"10.1111\/cge.13855"},{"key":"e_1_2_8_225_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2023.1219045"},{"key":"e_1_2_8_226_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13048-022-00971-9"},{"key":"e_1_2_8_227_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0051540"},{"key":"e_1_2_8_228_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41374-021-00671-w"},{"key":"e_1_2_8_229_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.865103"},{"key":"e_1_2_8_230_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-018-1188-3"},{"key":"e_1_2_8_231_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202303009"},{"key":"e_1_2_8_232_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.13-244111"},{"key":"e_1_2_8_233_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12396"},{"key":"e_1_2_8_234_1","doi-asserted-by":"publisher","DOI":"10.1080\/15384101.2023.2275907"},{"key":"e_1_2_8_235_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.042747"},{"key":"e_1_2_8_236_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2008.01.013"},{"key":"e_1_2_8_237_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-021-02219-9"},{"key":"e_1_2_8_238_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202413097"},{"key":"e_1_2_8_239_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232112961"},{"key":"e_1_2_8_240_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-022-04447-3"}],"container-title":["Cytoskeleton"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cm.70062","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cm.70062","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cm.70062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T19:11:14Z","timestamp":1787080274000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cm.70062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,31]]},"references-count":239,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/cm.70062"],"URL":"https:\/\/doi.org\/10.1002\/cm.70062","archive":["Portico"],"relation":{},"ISSN":["1949-3584","1949-3592"],"issn-type":[{"value":"1949-3584","type":"print"},{"value":"1949-3592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,31]]},"assertion":[{"value":"2025-05-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}