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In this study, a low toxicity, biocompatible, therapeutic, and observable GH\u2013nanoparticle complex for specifically targeting growth hormone receptor (GHR) in cancer cells was synthesized by conjugating GH with green fluorescence protein and carboxylated nanodiamond. Moreover, we have shown that this complex can be triggered by laser irradiation to create a \u201cnanoblast\u201d and induce cell death in the A549 non\u2010small\u2010cell lung cancer cell line via the apoptotic pathway. 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