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The heterocyclic N atom nearest to the Cl atom and the N\n                    <jats:sub>sulfonamide<\/jats:sub>\n                    atom could be coordination sites for the silver ion in the Ag\u2013SCP\u2013SCN complex. The Ag\u2013SCP complex is a polymeric compound with metal\u2013metal bonds, and the heterocyclic and sulfonamide N atoms are points of coordination for Ag\n                    <jats:sup>I<\/jats:sup>\n                    . Both complexes showed activity against all the tested bacteria, and in the cases of\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    , the action was better than that of SCP. In all cases, both silver\u2013SCP complexes showed better antifungal activity than SCP, which was inactive against the tested fungi. Notably, the activity against\n                    <jats:italic>P.\u2005aeruginosa<\/jats:italic>\n                    , a nosocomial multidrug\u2010resistant pathogen, was better than that of the reference antibiotic cefotaxim. Both silver\u2013sulfa complexes displayed moderate activity against the tested yeast, especially for\n                    <jats:italic>C.\u2005neoformans<\/jats:italic>\n                    , which is an important fact considering the incidence of cryptococcosis, mainly in immune\u2010deficient patients. No chromosomal aberrations were observed with the\n                    <jats:italic>Allium cepa<\/jats:italic>\n                    test, which is auspicious for further study of these complexes as potential drugs.\n                  <\/jats:p>","DOI":"10.1002\/cmdc.201400071","type":"journal-article","created":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T09:28:36Z","timestamp":1399454916000},"page":"1211-1220","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Antibacterial, Antifungal, Phytotoxic, and Genotoxic Properties of Two Complexes of Ag\n                    <sup>I<\/sup>\n                    with Sulfachloropyridazine (SCP): X\u2010ray Diffraction of [Ag(SCP)]\n                    <sub>\n                      <i>n<\/i>\n                    <\/sub>"],"prefix":"10.1002","volume":"9","author":[{"given":"Natalia","family":"Mosconi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Giulidori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Velluti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estela","family":"Hure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agustina","family":"Postigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graciela","family":"Borthagaray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davi Fernando","family":"Back","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda H.","family":"Torre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Rizzotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,7]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2009.01.025"},{"key":"e_1_2_6_2_2","volume-title":"ACS Symposium Series No.\u2005903: Medicinal Inorganic Chemistry","year":"2005"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.poly.2012.04.017"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.poly.2010.11.025"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2006.08.019"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/1040841X.2012.713323"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr300288v"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-6445(03)00047-0"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2010.03.014"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2013.12.014"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jorganchem.2013.10.035"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2012.07.044"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2014.01.033"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00775-014-1089-6"},{"key":"e_1_2_6_15_2","first-page":"261","volume-title":"Metal Ions in Biological Systems Vol.\u200516: Methods Involving Metal Ions and Complexes in Clinical Chemistry","author":"Bult A.","year":"1983"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ica.2006.03.030"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2012.09.064"},{"key":"e_1_2_6_18_2","volume-title":"Las bases Farmacol\u00f3gicas de La Terap\u00e9utica","author":"Goodman A. 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