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The fluorine\u201018 prosthetic group was prepared from its toluenesulfonate precursor and isolated in 21\u201335\u2009% radiochemical yield in 30\u2005minutes of synthetic time. ADIBO\u2010F has been incorporated into azide\u2010functionalized, cancer\u2010targeting peptides through a strain\u2010promoted alkyne\u2013azide cycloaddition with high radiochemical yields and purities. The final products are novel peptide\u2010based positron emission tomography (PET) imaging agents that possess high affinities for their targets, growth hormone secretagogue receptor\u20051a (GHSR\u20101a) and gastrin\u2010releasing peptide receptor (GRPR), with IC<jats:sub>50<\/jats:sub> values of 9.7 and 0.50\u2005n<jats:sc>m<\/jats:sc>, respectively. 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