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Compared with plain copper, these nanostructured copper surfaces with Cu(OH)<jats:sub>2<\/jats:sub> nano\u2010sword or CuO nano\u2010foam were found to completely eliminate pathogens at a fast rate, including clinically isolated drug resistant species. Additionally these nanostructured copper surfaces demonstrated potential antiviral properties when assessed against bacteriophages, as a viral surrogate, and murine hepatitis virus, a surrogate for SARS\u2010CoV\u20102. The multiple modes of killing, physical killing and copper ion mediated killing contribute to the superior and fast kinetics of antimicrobial action against common microbes, and ESKAPE pathogens. Prototypes for air and water cleaning with current nanostructured copper surface have also been demonstrated.<\/jats:p>","DOI":"10.1002\/cmdc.202100504","type":"journal-article","created":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T22:06:46Z","timestamp":1630274806000},"page":"3553-3558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Nanostructured Copper Surface Kills ESKAPE Pathogens and Viruses in Minutes"],"prefix":"10.1002","volume":"16","author":[{"given":"Guangshun","family":"Yi","sequence":"first","affiliation":[{"name":"Institute of Bioengineering and Bioimaging  31 Biopolis Way, The Nanos Singapore 138669"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siti Nurhanna","family":"Riduan","sequence":"additional","affiliation":[{"name":"Institute of Bioengineering and Bioimaging  31 Biopolis Way, The Nanos Singapore 138669"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arunmozhiarasi","family":"Armugam","sequence":"additional","affiliation":[{"name":"Institute of Bioengineering and Bioimaging  31 Biopolis Way, The Nanos Singapore 138669"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Ting","family":"Ong","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases  16 Jalan Tan Tock Seng Singapore 308442"},{"name":"Tan Tock Seng Hospital  11 Jalan Tan Tock Seng Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei Yun","family":"Hon","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases  16 Jalan Tan Tock Seng Singapore 308442"},{"name":"Tan Tock Seng Hospital  11 Jalan Tan Tock Seng Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Yazid","family":"Abdad","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases  16 Jalan Tan Tock Seng Singapore 308442"},{"name":"Tan Tock Seng Hospital  11 Jalan Tan Tock Seng Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shawn","family":"Vasoo","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases  16 Jalan Tan Tock Seng Singapore 308442"},{"name":"Tan Tock Seng Hospital  11 Jalan Tan Tock Seng Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda SP","family":"Ang","sequence":"additional","affiliation":[{"name":"National Centre for Infectious Diseases  16 Jalan Tan Tock Seng Singapore 308442"},{"name":"Tan Tock Seng Hospital  11 Jalan Tan Tock Seng Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yugen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Bioengineering and Bioimaging  31 Biopolis Way, The Nanos Singapore 138669"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,24]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"WHO WHO Director-General's opening remarks at the media briefing on COVID-19 https:\/\/www.who.int\/dg\/speeches\/detail\/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19-11-march-2020 accessed."},{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30567-5"},{"key":"e_1_2_2_3_1","doi-asserted-by":"crossref","unstructured":"P.\u2005Y. 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