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Changes in m<jats:sup>6<\/jats:sup>A levels in transcriptome are tightly correlated to expression levels of m<jats:sup>6<\/jats:sup>A methyltransferases and demethylases. Abnormal expression levels of methyltransferases and demethylases are observed in various diseases and health conditions such as cancer, male infertility, and obesity. This research explores the efficacy of m<jats:sup>6<\/jats:sup>A\u2010modified RNA as an anticancer drug target. We discovered a 12\u2010mer peptide that binds specifically to m<jats:sup>6<\/jats:sup>A\u2010modified RNA using phage display experiments. Our fluorescence\u2010based assays illustrate the selected peptide binds to methylated RNA with lower micromolar affinity and inhibit the binding of protein FTO, a demethylase enzyme specific to m<jats:sup>6<\/jats:sup>A modification. When cancer cell lines were treated with mtp1, it led to an increase in m<jats:sup>6<\/jats:sup>A levels and a decrease in cell viability. 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