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Besides its role in physiological and pathophysiological conditions, the promising therapeutic potential of this small\u2010molecule makes it advantageous for various pharmaceutical applications. The endogenous production of H\n                    <jats:sub>2<\/jats:sub>\n                    S at a lower concentration is crucial in maintaining redox balance and cellular homeostasis, and the dysregulation leads to various disease states. In the event of H\n                    <jats:sub>2<\/jats:sub>\n                    S deficiency, the exogenous donation of H\n                    <jats:sub>2<\/jats:sub>\n                    S could help maintain the optimal cellular concentration of H\n                    <jats:sub>2<\/jats:sub>\n                    S and cellular homeostasis. Over the last several years, researchers have developed numerous small\u2010molecule non\u2010fluorogenic organosulfur compounds as H\n                    <jats:sub>2<\/jats:sub>\n                    S donors and investigated their pharmacological potentials. However, reports on stimuli\u2010responsive turn\u2010on fluorogenic donors of H\n                    <jats:sub>2<\/jats:sub>\n                    S have appeared recently. Interestingly, the fluorogenic H\n                    <jats:sub>2<\/jats:sub>\n                    S donors offer additional advantages with the non\u2010invasive real\u2010time monitoring of the H\n                    <jats:sub>2<\/jats:sub>\n                    S release utilizing the simultaneous turn\u2010on fluorogenic processes. The review summarizes the recent developments in turn\u2010on fluorogenic donors of H\n                    <jats:sub>2<\/jats:sub>\n                    S and the potential biological applications that have developed over the years.\n                  <\/jats:p>","DOI":"10.1002\/cmdc.202400251","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T03:42:57Z","timestamp":1715744577000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Recent Developments On Activatable Turn\u2010On Fluorogenic Donors of Hydrogen Sulfide (H\n                    <sub>2<\/sub>\n                    S)"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8564-8415","authenticated-orcid":false,"given":"Roopjyoti","family":"Misra","sequence":"first","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Guwahati  Guwahati 781039 Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6628-7323","authenticated-orcid":false,"given":"Hirak Jyoti","family":"Bhuyan","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Guwahati  Guwahati 781039 Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5048-3278","authenticated-orcid":false,"given":"Amlan","family":"Dutta","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Guwahati  Guwahati 781039 Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9115-7561","authenticated-orcid":false,"given":"Krishna P.","family":"Bhabak","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Guwahati  Guwahati 781039 Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"key":"e_1_2_7_1_1","unstructured":"\u00a0"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00205"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2017.11.014"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00212A"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2017.7058"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12081644"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0211hyp"},{"key":"e_1_2_7_9_1","unstructured":"\u00a0"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/15216540500217875"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2010.10.705"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.21.6008"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1139\/Y07-120"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.105.092023"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.199919"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc5162"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.2882"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2014.5901"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5309"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034562"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2009.09.018"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R110.128363"},{"key":"e_1_2_7_23_1","unstructured":"\u00a0"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R400005200"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C400481200"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2008.2253"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2021.05.010"},{"key":"e_1_2_7_28_1","first-page":"1899","volume":"11","author":"Magli E.","year":"2021","journal-title":"Biomol. 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