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This study reports the synthesis and application of a chitosan\u2010polyethylene glycol\u2010folic acid (CTS\u2010PEG\u2010FA) conjugate as a functional liposome coating. The CTS\u2010PEG\u2010FA conjugate is synthesized and thoroughly characterized using spectroscopic techniques. Liposomes coated with this polymer are prepared via the thin\u2010film hydration method and analyzed for particle size, zeta potential, and morphology through transmission electron microscopy. Using quercetin as a model drug, the system's drug\u2010loading capacity and release kinetics are investigated. Results demonstrate that CTS\u2010PEG\u2010FA\u2010coated liposomes facilitate enhanced cellular uptake and exhibit promising cytotoxic effects in cancer cells. 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