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Initially, the drug remdesivir is approved by the FDA for the treatment of SARS\u2010CoV\u20102. Significant efforts have been directed toward epidemiology of the SARS\u2010CoV\u20102 virus to discover potential drug targets that may contribute to the development of effective prevention and treatment strategies. The structure and functions of SARS\u2010CoV\u20102 proteins that may be potential drug targets, including the spike protein, main protease, papain\u2010like protease, RNA\u2010dependent RNA polymerase, host proteins like angiotensin\u2010converting enzyme 2, and transmembrane protease and serine 2, have been thoroughly studied. Biological screening platforms and repurposing have resulted in the discovery of drugs such as nirmatrelvir\u2010ritonavir (Paxlovid), remdesivir (Veklury), molnupiravir (Lagevrio), anakinra (Kineret), vilobelimab (Gohibic), baricitinib (Olumiant), and tocilizumab (Actemra). 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