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Inappropriate wound care and excessive use of antibiotics often compromise treatment outcomes, leading to the emergence of antimicrobial resistance. Hence, development of novel, more effective treatment strategies is essential to reduce infection\u2010associated mortality and minimize treatment\u2010related side effects. Recently, antibacterial photodynamic therapy (aPDT) has attracted considerable attention for the management of infected wounds. Several studies have investigated the application of aPDT for wound healing using in vivo animal models. aPDT effectively eliminates pathogenic bacteria while also promoting fibroblast proliferation and accelerating tissue regeneration and wound repair. To further improve aPDT efficiency, the development of advanced photosensitizers (PSs) has become a key research focus. Recently, metal\u2010based PSs have attracted significant attention owing to their strong light absorption, long\u2010lived excited states, and efficient generation of reactive oxygen species (ROS), which enhance light\u2010triggered antimicrobial activity. Despite these promising properties, their application in the healing of infected wounds remains largely underexplored, with only a few reports to date. This highlights an important opportunity to further develop metal\u2010based PSs as effective aPDT agents for wound treatment. Therefore, this perspective critically discusses recent advances and outlines future directions for developing more effective PDT\u2010assisted wound\u2010healing strategies.<\/jats:p>","DOI":"10.1002\/cmdc.70479","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T05:07:06Z","timestamp":1789103226000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metal\u2010Based Photosensitizers as Emerging Antibacterial Agents for Infected Wound Healing"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3645-1029","authenticated-orcid":false,"given":"Arif Ali","family":"Mandal","sequence":"first","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology (BHU)  Varanasi Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4919-408X","authenticated-orcid":false,"given":"Bhaskar 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