{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:57:16Z","timestamp":1790567836396,"version":"4.1.0"},"reference-count":256,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemMedChem"],"published-print":{"date-parts":[[2026,9,28]]},"abstract":"<jats:p>Malaria and leishmaniasis continue to impose a substantial health burden, while current therapeutic and diagnostic strategies remain limited by toxicity, prolonged regimens, drug resistance, and restricted field applicability. This review examines recent advances in peptide\u2010enabled nanoplatforms for both diseases, with emphasis on intracellular targeting, drug delivery, and diagnostic innovation. Antimicrobial peptides, cell\u2010penetrating peptides, peptoids, mimotopes, and peptide\u2010functionalized nanocarriers have been explored to improve parasite targeting, intracellular delivery, pharmacokinetics, and antiparasitic efficacy. In parallel, peptide\u2010 and aptamer\u2010based nanosensors have expanded the detection of clinically relevant biomarkers, including HRP2, pLDH, GP63, KMP\u201011, and kDNA, highlighting their potential for sensitive and modular diagnostics. Despite these advances, translation remains constrained by limited in vivo validation, insufficient pharmacokinetic standardization, incomplete toxicity profiling, poor batch reproducibility, protein corona\u2010associated variability, and scarce validation under field\u2010relevant conditions. Peptide\u2010enabled nanoplatforms are therefore most likely to succeed when aligned with stage\u2010specific parasite biology, realistic host cell\u2010targeting requirements, and scalable implementation pathways in endemic settings.<\/jats:p>","DOI":"10.1002\/cmdc.70493","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:16:08Z","timestamp":1789625768000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Peptide\u2010Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6694-7991","authenticated-orcid":false,"given":"Christian S.","family":"Carnero Canales","sequence":"first","affiliation":[{"name":"BIOMET Laboratorio de Qu\u00edmica Bioinorg\u00e1nica en Medicina Medioambiente y Tecnolog\u00eda Facultad de Ciencias de la Universidad Nacional de Ingenier\u00eda  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1777-7699","authenticated-orcid":false,"given":"Ana Clara","family":"Lunardi Yagi","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences S\u00e3o Paulo State University (UNESP)  Araraquara Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1827-9102","authenticated-orcid":false,"given":"T\u00falio Cust\u00f3dio","family":"Reis","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences S\u00e3o Paulo State University (UNESP)  Araraquara Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3736-1654","authenticated-orcid":false,"given":"Jessica Ingrid","family":"Cazorla","sequence":"additional","affiliation":[{"name":"General humanidades Universidad Continental (UC)  Arequipa Per\u00fa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jade","family":"Rojas Villar","sequence":"additional","affiliation":[{"name":"School of Pharmacy Biochemistry and Biotechnology Universidad Cat\u00f3lica Santa Mar\u00eda (UCSM)  Arequipa Per\u00fa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia A.","family":"Graminha","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences S\u00e3o Paulo State University (UNESP)  Araraquara Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana Yesenia","family":"Pastrana Alta","sequence":"additional","affiliation":[{"name":"BIOMET Laboratorio de Qu\u00edmica Bioinorg\u00e1nica en Medicina Medioambiente y Tecnolog\u00eda Facultad de Ciencias de la Universidad Nacional de Ingenier\u00eda  Lima Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6969-3963","authenticated-orcid":false,"given":"Fernando Rog\u00e9rio","family":"Pavan","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences S\u00e3o Paulo State University (UNESP)  Araraquara Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392\u2010025\u201002246\u20103"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2211803"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666\u20105247(24)00172\u20101"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010025\u201005350\u20105"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2024.105489"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010022\u201000726\u20108"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15010099"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2022.2074130"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2022.174934"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2025.04.004"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249\u2010024\u201001260\u2010x"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s44197\u2010024\u201000228\u20102"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanmic.2025.101073"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071\u2010025\u201006796\u2010x"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0012668"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-025-00663-w"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines13111082"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201050405\u2010x"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0011978"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0013302"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2026.101362"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(24)00141\u20105"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.5599\/admet.2992"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249\u2010025\u201001368\u20108"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182025101467"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2025.107800"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0013321"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2022.04.004"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2023.114733"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2024.115239"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2025.2522245"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951\u2010022\u201001709\u2010x"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2024.126828"},{"key":"e_1_2_14_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00604\u2010023\u201005891\u2010z"},{"key":"e_1_2_14_36_1","unstructured":"A. S.Gozalo C. K.Robinson J.Holdridge O. L.Franco Mahecha andW. R.Elkins American Association for Laboratory Animal Science preprint 2024 https:\/\/doi.org\/10.30802\/AALAS\u2010CM\u201024\u2010000019"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2022.2150456"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010micro\u2010041320\u2010020659"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a025452"},{"key":"e_1_2_14_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579\u2010024\u201001008\u20102"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2018.11.010"},{"key":"e_1_2_14_42_1","unstructured":"About Malaria Malaria CDC n.d (accessed 28 November 2025) https:\/\/www.cdc.gov\/malaria\/about\/index.html."},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102958.2002.03057.x"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2024.2429617"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201027109\u20107"},{"key":"e_1_2_14_46_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20110575"},{"key":"e_1_2_14_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12745"},{"key":"e_1_2_14_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24244559"},{"key":"e_1_2_14_49_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.816574"},{"key":"e_1_2_14_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2025.111702"},{"key":"e_1_2_14_51_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.5c11292"},{"key":"e_1_2_14_52_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.3c00147"},{"key":"e_1_2_14_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201051267\u20105"},{"key":"e_1_2_14_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10121560"},{"key":"e_1_2_14_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s11671\u2010026\u201004695\u20103"},{"key":"e_1_2_14_56_1","unstructured":"Leishmaniasis n.d. (Accessed 28 November 2025) https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/leishmaniasis."},{"key":"e_1_2_14_57_1","unstructured":"Leishmaniasis \u2010 PAHO\/WHO | Pan American Health Organization n.d. (Accessed 28 November 2025)https:\/\/www.paho.org\/en\/topics\/leishmaniasis."},{"key":"e_1_2_14_58_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research"},{"key":"e_1_2_14_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253\u2010020\u201010856\u2010w"},{"key":"e_1_2_14_60_1","doi-asserted-by":"publisher","DOI":"10.1080\/21678707.2024.2335248"},{"key":"e_1_2_14_61_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.4c00010"},{"key":"e_1_2_14_62_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035671"},{"key":"e_1_2_14_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2025.123779"},{"key":"e_1_2_14_64_1","doi-asserted-by":"publisher","DOI":"10.1242\/JCS.226183\/VIDEO\u20102"},{"key":"e_1_2_14_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201000443\u2010y"},{"key":"e_1_2_14_66_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02529"},{"key":"e_1_2_14_67_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00248\u201022"},{"key":"e_1_2_14_68_1","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed8050276"},{"key":"e_1_2_14_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.2016.283.issue\u20104"},{"key":"e_1_2_14_70_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.10.19"},{"key":"e_1_2_14_71_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18061296"},{"key":"e_1_2_14_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2019.10.008"},{"key":"e_1_2_14_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2608"},{"key":"e_1_2_14_74_1","doi-asserted-by":"publisher","DOI":"10.21767\/1791\u2010809x.1000519"},{"key":"e_1_2_14_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40475\u2010021\u201000232\u20107"},{"key":"e_1_2_14_76_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1678\u20109946202264051"},{"key":"e_1_2_14_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11686\u2010023\u201000695\u2010w"},{"key":"e_1_2_14_78_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10101887"},{"key":"e_1_2_14_79_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_602_20"},{"key":"e_1_2_14_80_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071\u2010019\u20103723\u20101"},{"key":"e_1_2_14_81_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9040759"},{"key":"e_1_2_14_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2021.183629"},{"key":"e_1_2_14_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/feb4.v13.3"},{"key":"e_1_2_14_84_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2025.1573618"},{"key":"e_1_2_14_85_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006052"},{"key":"e_1_2_14_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpddr.2024.100574"},{"key":"e_1_2_14_87_1","doi-asserted-by":"publisher","DOI":"10.3389\/fitd.2022.837460"},{"key":"e_1_2_14_88_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M605214200"},{"key":"e_1_2_14_89_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.8.2397\u20102403.2003"},{"key":"e_1_2_14_90_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104\u2010019\u20104784\u20100"},{"key":"e_1_2_14_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2024.107315"},{"key":"e_1_2_14_92_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004087"},{"key":"e_1_2_14_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lansea.2023.100317"},{"key":"e_1_2_14_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.05.023"},{"key":"e_1_2_14_95_1","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20200176"},{"key":"e_1_2_14_96_1","unstructured":"J. M. J.Verhoef M.Meissner andT. W. A.Kooij American Society for Microbiology preprint 2021 https:\/\/doi.org\/10.1128\/mBio.01409\u201021"},{"key":"e_1_2_14_97_1","volume-title":"Heliyon","author":"Abugri J.","year":"2022"},{"key":"e_1_2_14_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2020.107987"},{"key":"e_1_2_14_99_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0011635"},{"key":"e_1_2_14_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmr.2025.100104"},{"key":"e_1_2_14_101_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.582779"},{"key":"e_1_2_14_102_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms13112574"},{"key":"e_1_2_14_103_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14030642"},{"key":"e_1_2_14_104_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2018.00204"},{"key":"e_1_2_14_105_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202503964"},{"key":"e_1_2_14_106_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.668632"},{"key":"e_1_2_14_107_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9010024"},{"key":"e_1_2_14_108_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5RA02745D"},{"key":"e_1_2_14_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cis.2017.01.005"},{"key":"e_1_2_14_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2021.101229"},{"key":"e_1_2_14_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2023.121449"},{"key":"e_1_2_14_112_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.710199"},{"key":"e_1_2_14_113_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13111795"},{"key":"e_1_2_14_114_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom11070984"},{"key":"e_1_2_14_115_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436\u2010024\u201008133\u20100"},{"key":"e_1_2_14_116_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.03339\u201023"},{"key":"e_1_2_14_117_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens12070939"},{"key":"e_1_2_14_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2025.102381"},{"key":"e_1_2_14_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2024.125163"},{"key":"e_1_2_14_120_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0TB01398F"},{"key":"e_1_2_14_121_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.2c00632"},{"key":"e_1_2_14_122_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1437430"},{"key":"e_1_2_14_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2024.124746"},{"key":"e_1_2_14_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111920"},{"key":"e_1_2_14_125_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics16020240"},{"key":"e_1_2_14_126_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules30071572"},{"key":"e_1_2_14_127_1","doi-asserted-by":"publisher","DOI":"10.34133\/bmef.0104"},{"key":"e_1_2_14_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2025.101289"},{"key":"e_1_2_14_129_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5NR00617A"},{"key":"e_1_2_14_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.01.038"},{"key":"e_1_2_14_131_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2307800120"},{"key":"e_1_2_14_132_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202411720"},{"key":"e_1_2_14_133_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics17091123"},{"key":"e_1_2_14_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2023.115139"},{"key":"e_1_2_14_135_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4TB02144D"},{"key":"e_1_2_14_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2024.123844"},{"key":"e_1_2_14_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2024.123805"},{"key":"e_1_2_14_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.07.014"},{"key":"e_1_2_14_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2023.114904"},{"key":"e_1_2_14_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.113940"},{"key":"e_1_2_14_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2021.04.006"},{"key":"e_1_2_14_142_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41565\u2010024\u201001754\u20107"},{"key":"e_1_2_14_143_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2019.00415"},{"key":"e_1_2_14_144_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3AN01739G"},{"key":"e_1_2_14_145_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1NR06342A"},{"key":"e_1_2_14_146_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4CS00507D"},{"key":"e_1_2_14_147_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c13214"},{"key":"e_1_2_14_148_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5c08608"},{"key":"e_1_2_14_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2023.103046"},{"key":"e_1_2_14_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2024.114611"},{"key":"e_1_2_14_151_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201048838\u20105"},{"key":"e_1_2_14_152_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c08922"},{"key":"e_1_2_14_153_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201045254\u20107"},{"key":"e_1_2_14_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2025.101922"},{"key":"e_1_2_14_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2025.102343"},{"key":"e_1_2_14_156_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13346\u2010021\u201001024\u20102"},{"key":"e_1_2_14_157_1","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1892"},{"key":"e_1_2_14_158_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951\u2010025\u201003921\u2010x"},{"key":"e_1_2_14_159_1","doi-asserted-by":"publisher","DOI":"10.1080\/17435889.2025.2552099"},{"key":"e_1_2_14_160_1","doi-asserted-by":"publisher","DOI":"10.1088\/1748\u2010605X\/ad4aaa"},{"key":"e_1_2_14_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.114115"},{"key":"e_1_2_14_162_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0012242"},{"key":"e_1_2_14_163_1","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.202100046"},{"key":"e_1_2_14_164_1","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1943"},{"key":"e_1_2_14_165_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c08005"},{"key":"e_1_2_14_166_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392\u2010024\u201002107\u20105"},{"key":"e_1_2_14_167_1","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2025.2554079"},{"key":"e_1_2_14_168_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12010\u2010021\u201003621\u2010w"},{"key":"e_1_2_14_169_1","doi-asserted-by":"publisher","DOI":"10.30466\/vrf.2025.2047654.4572"},{"key":"e_1_2_14_170_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit378"},{"key":"e_1_2_14_171_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1122411"},{"key":"e_1_2_14_172_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S420832"},{"key":"e_1_2_14_173_1","doi-asserted-by":"publisher","DOI":"10.3390\/app11052284"},{"key":"e_1_2_14_174_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13223470"},{"key":"e_1_2_14_175_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010022\u201007204\u2010w"},{"key":"e_1_2_14_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrp.2024.101801"},{"key":"e_1_2_14_177_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4NA00214H"},{"key":"e_1_2_14_178_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41564\u2010018\u20100295\u20103"},{"key":"e_1_2_14_179_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h5527"},{"key":"e_1_2_14_180_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-821100-7.00024-8"},{"key":"e_1_2_14_181_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma14216319"},{"key":"e_1_2_14_182_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41564\u2010021\u201000962\u20104"},{"key":"e_1_2_14_183_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-20521-7_4"},{"key":"e_1_2_14_184_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781394175222.ch7"},{"key":"e_1_2_14_185_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40001\u2010025\u201002685\u20102"},{"key":"e_1_2_14_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2021.130812"},{"key":"e_1_2_14_187_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201019755\u20100"},{"key":"e_1_2_14_188_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.958693"},{"key":"e_1_2_14_189_1","doi-asserted-by":"publisher","DOI":"10.1111\/pim.12824"},{"key":"e_1_2_14_190_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes9120584"},{"key":"e_1_2_14_191_1","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1675"},{"key":"e_1_2_14_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2024.116352"},{"key":"e_1_2_14_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2023.108958"},{"key":"e_1_2_14_194_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics12111046"},{"key":"e_1_2_14_195_1","first-page":"783","volume-title":"Advances in Medical Imaging, Detection, and Diagnosis","author":"Jain S.","year":"2023"},{"key":"e_1_2_14_196_1","doi-asserted-by":"publisher","DOI":"10.3390\/s23020562"},{"key":"e_1_2_14_197_1","doi-asserted-by":"publisher","DOI":"10.3390\/s24237432"},{"key":"e_1_2_14_198_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.3c01965"},{"key":"e_1_2_14_199_1","first-page":"1","article-title":"A Critical Review on the Identification of Pathogens by Employing Peptide\u2010Based Electrochemical Biosensors","volume":"56","author":"Premchanth Jyothi S.","year":"2024","journal-title":"Critical Reviews in Analytical Chemistry"},{"key":"e_1_2_14_200_1","doi-asserted-by":"publisher","DOI":"10.3390\/bios11110418"},{"key":"e_1_2_14_201_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010024\u201010173\u2010x"},{"key":"e_1_2_14_202_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182014001280"},{"key":"e_1_2_14_203_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2023.07.045"},{"key":"e_1_2_14_204_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c05750"},{"key":"e_1_2_14_205_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202501431"},{"key":"e_1_2_14_206_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2024.05.013"},{"key":"e_1_2_14_207_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201068231\u2010y"},{"key":"e_1_2_14_208_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010019\u20103010\u20109"},{"key":"e_1_2_14_209_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201092723\u2010w"},{"key":"e_1_2_14_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2024.104047"},{"key":"e_1_2_14_211_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25094870"},{"key":"e_1_2_14_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.08.132"},{"key":"e_1_2_14_213_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2024.1446626"},{"key":"e_1_2_14_214_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00726\u2010025\u201003454\u20105"},{"key":"e_1_2_14_215_1","doi-asserted-by":"publisher","DOI":"10.1002\/psc.70013"},{"key":"e_1_2_14_216_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2024.115633"},{"key":"e_1_2_14_217_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0011975"},{"key":"e_1_2_14_218_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2026.102685"},{"key":"e_1_2_14_219_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2022.107962"},{"key":"e_1_2_14_220_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00726\u2010023\u201003245\u2010w"},{"key":"e_1_2_14_221_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2024.107137"},{"key":"e_1_2_14_222_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph16030439"},{"key":"e_1_2_14_223_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adx0153"},{"key":"e_1_2_14_224_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms252413241"},{"key":"e_1_2_14_225_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12248\u2010023\u201000819\u20100"},{"key":"e_1_2_14_226_1","doi-asserted-by":"publisher","DOI":"10.1039\/D6SC02646J"},{"key":"e_1_2_14_227_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010025\u201059665\u20107"},{"key":"e_1_2_14_228_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.61747"},{"key":"e_1_2_14_229_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics17050616"},{"key":"e_1_2_14_230_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936\u2010024\u201004986\u2010z"},{"key":"e_1_2_14_231_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.adh9902"},{"key":"e_1_2_14_232_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2023.103714"},{"key":"e_1_2_14_233_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2026.115925"},{"key":"e_1_2_14_234_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2021.11.042"},{"key":"e_1_2_14_235_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c02277"},{"key":"e_1_2_14_236_1","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2022.2093854"},{"key":"e_1_2_14_237_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.3c01494"},{"key":"e_1_2_14_238_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201044074\u20105"},{"key":"e_1_2_14_239_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.2c00132"},{"key":"e_1_2_14_240_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.3c05057"},{"key":"e_1_2_14_241_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5c15613"},{"key":"e_1_2_14_242_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2022.114587"},{"key":"e_1_2_14_243_1","doi-asserted-by":"publisher","DOI":"10.1002\/chir.v36.3"},{"key":"e_1_2_14_244_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11095\u2010023\u201003493\u20101"},{"key":"e_1_2_14_245_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2022.103464"},{"key":"e_1_2_14_246_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2025.10.026"},{"key":"e_1_2_14_247_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0012339"},{"key":"e_1_2_14_248_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5CC02322J"},{"key":"e_1_2_14_249_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44222\u2010024\u201000152\u2010x"},{"key":"e_1_2_14_250_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI185430"},{"key":"e_1_2_14_251_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2025.123927"},{"key":"e_1_2_14_252_1","doi-asserted-by":"publisher","DOI":"10.1002\/pro.v33.7"},{"key":"e_1_2_14_253_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00973\u201022"},{"key":"e_1_2_14_254_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2026.115679"},{"key":"e_1_2_14_255_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010025\u201006321\u20109"},{"key":"e_1_2_14_256_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c13388"},{"key":"e_1_2_14_257_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4NR02931C"}],"container-title":["ChemMedChem"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cmdc.70493","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cmdc.70493","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cmdc.70493","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:40:43Z","timestamp":1790566843000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/cmdc.70493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,16]]},"references-count":256,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2026,9,28]]}},"alternative-id":["10.1002\/cmdc.70493"],"URL":"https:\/\/doi.org\/10.1002\/cmdc.70493","archive":["Portico"],"relation":{},"ISSN":["1860-7179","1860-7187"],"issn-type":[{"value":"1860-7179","type":"print"},{"value":"1860-7187","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,16]]},"assertion":[{"value":"2026-06-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70493"}}