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The purpose of this study was to evaluate through a randomized controlled trial the effectiveness of a problem\u2010solving training intervention designed to empower women with breast carcinoma to cope with a range of difficulties when diagnosed in mid\u2010life.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>The study population consisted of women aged 50 years or younger who had no prior history of breast carcinoma, were diagnosed with Stage I\u2010IIIA tumors, and for whom a first course of chemotherapy had been initiated recently. The intervention consisted of two in\u2010person and four telephone sessions with an oncology nurse who provided problem\u2010solving skills training and informational materials to the women over a 12\u2010week period. All subjects were assessed for physical and psychosocial adjustment through telephone and mailed surveys at baseline, at 4 \u2013months, and at 8 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Of 183 eligible women, 164 participated (a 90% participation rate), 149 of whom completed the study (a 91% completion rate). The subjects had significantly lower unmet needs and better mental health at the 4\u2010month assessment. The intervention significantly decreased the number and severity of difficulties experienced by women with average or good problem\u2010solving skills at 8 months, but was not effective in alleviating or resolving the problems encountered by women with poor problem\u2010solving skills, relative to the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>We conclude that this problem\u2010solving therapy\u2010based home care training intervention is an effective method of helping the majority of women with breast carcinoma to reduce the stresses associated with the diagnosis and treatment of cancer in mid\u2010life. Cancer 2002;94:3089\u2013100. \u00a9 2002 American Cancer Society.<\/jats:p><jats:p>DOI 10.1002\/cncr.10586<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.10586","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T08:29:56Z","timestamp":1033892996000},"page":"3089-3100","source":"Crossref","is-referenced-by-count":127,"title":["A problem\u2010solving approach to stress reduction among younger women with breast carcinoma"],"prefix":"10.1002","volume":"94","author":[{"given":"Susan M.","family":"Allen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann C.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur M.","family":"Nezu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine 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