{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:44:49Z","timestamp":1761057889314,"version":"build-2065373602"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,1,8]],"date-time":"2004-01-08T00:00:00Z","timestamp":1073520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2004,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Breast Imaging Reporting and Data System (BI\u2010RADS) Category 3 represents \u2018probably benign\u2019 mammographic abnormalities requiring close follow\u2010up, but biopsies sometimes are performed on Category 3 abnormalities. Controversy exists as to when these biopsies are justified. The goals of the current study were to evaluate the use of stereotactic vacuum\u2010assisted breast biopsy (SVABB) for BI\u2010RADS 3 lesions in a nonacademic community hospital\u2013based practice, to evaluate the false\u2010 negative rate of Category 3 mammograms, and to determine whether any specific lesions misinterpreted as BI\u2010RADS 3 abnormalities might commonly be associated with malignant disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>From August 2000 to December 2002, the authors performed 947 SVABB procedures on 911 patients. They focused on 156 SVABBs of BI\u2010RADS 3 abnormalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Of 634 SVABB procedures requested by outside sources, 114 (18%) were performed for BI\u2010RADS 3 abnormalities, compared with 42 (13%) of 313 SVABB procedures that were performed based on mammographic findings at the authors' practice (<jats:italic>P<\/jats:italic> = 0.075). After SVABB, 7 of 156 patients with BI\u2010RADS 3 lesions were diagnosed with breast carcinoma and 1 was diagnosed with atypical ductal hyperplasia. Therefore, the false\u2010negative rate of BI\u2010RADS 3 mammograms was 4.5% (i.e., 7 of 156 patients). Patients with linear microcalcifications had the highest rate of cancer (4 of 14 [29%]) compared with patients without microcalcifications (1 of 64 [1.5%]) and patients with nonlinear microcalcifications (2 of 69 [2.9%]).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The use of SVABB for BI\u2010RADS 3 lesions reflected uncertainty regarding the potential for a diagnosis of malignant disease rather than the financial incentive of performing a biopsy. SVABB was not necessary for patients with BI\u2010RADS 3 lesions without microcalcifications or for patients with nonlinear microcalcifications. Lesions with linear (casting or branching) microcalcifications should not be considered BI\u2010RADS 3 abnormalities. Cancer 2004;100:710\u20134. \u00a9 2004 American Cancer Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.20017","type":"journal-article","created":{"date-parts":[[2004,2,5]],"date-time":"2004-02-05T05:00:32Z","timestamp":1075957232000},"page":"710-714","source":"Crossref","is-referenced-by-count":17,"title":["Evaluation of Breast Imaging Reporting and Data System Category 3 mammograms and the use of stereotactic vacuum\u2010assisted breast biopsy in a nonacademic community practice"],"prefix":"10.1002","volume":"100","author":[{"given":"Angela","family":"Mendez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Cabanillas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Echenique","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keyvan","family":"Malekshamran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,2,3]]},"reference":[{"volume-title":"Breast imaging reporting and data system","year":"1998","author":"American College of Radiology","key":"e_1_2_5_2_2"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.188.2.8327670"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.190.2.313-a"},{"key":"e_1_2_5_5_2","first-page":"30","article-title":"Physician qualifications for stereotactic breast biopsy: a revised statement","volume":"83","author":"American College of Surgeons and American College of Radiology","year":"1998","journal-title":"Bull Am Coll Surg."},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.184.2.1620838"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.179.2.2014293"},{"key":"e_1_2_5_8_2","first-page":"223","article-title":"Level of suspicion of a mammographic lesion: use of features defined by BI\u2010RADS lexicon and correlation with large\u2010core breast biopsy","volume":"49","author":"Berube M","year":"1998","journal-title":"Can Assoc Radiol J."},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.177.3.1770559"},{"key":"e_1_2_5_10_2","first-page":"98","article-title":"Stereotactic breast biopsy: a six\u2010year surgical experience","volume":"99","author":"Tate PS","year":"2001","journal-title":"J Ky Med Assoc."},{"key":"e_1_2_5_11_2","first-page":"1063","article-title":"Stereotactic 11\u2010gauge directional vacuum\u2010assisted breast biopsy: experience with 249 patients","volume":"83","author":"Travade A","year":"2002","journal-title":"J Radiol."},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-16398"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcncr.20017","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.20017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T10:14:05Z","timestamp":1760264045000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.20017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2,3]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,2,15]]}},"alternative-id":["10.1002\/cncr.20017"],"URL":"https:\/\/doi.org\/10.1002\/cncr.20017","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"type":"print","value":"0008-543X"},{"type":"electronic","value":"1097-0142"}],"subject":[],"published":{"date-parts":[[2004,2,3]]}}}