{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T02:31:18Z","timestamp":1792031478918,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2005,2,14]],"date-time":"2005-02-14T00:00:00Z","timestamp":1108339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>The third edition of the International Classification of Diseases for Oncology (ICD\u2010O\u20103), which was published in 2000, introduced major changes in coding and classification of neoplasms, notably for leukemias and lymphomas, which are important groups of cancer types that occur in childhood. This necessitated a third revision of the 1996 International Classification of Childhood Cancer (ICCC\u20103).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The tumor categories for the ICCC\u20103 were designed to respect several principles: agreement with current international standards, integration of the entities defined by newly developed diagnostic techniques, continuity with previous childhood classifications, and exhaustiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The ICCC\u20103 classifies tumors coded according to the ICD\u2010O\u20103 into 12 main groups, which are split further into 47 subgroups. These 2 levels of the ICCC\u20103 allow standardized comparisons of the broad categories of childhood neoplasms in continuity with the previous classifications. The 16 most heterogeneous subgroups are broken down further into 2\u201311 divisions to allow study of important entities or homogeneous collections of tumors characterized at the cytogenetic or molecular level. Some divisions may be combined across the higher\u2010level categories, such as the B\u2010cell neoplasms within leukemias and lymphomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>The ICCC\u20103 respects currently existing international standards and was designed for use in international, population\u2010based, epidemiological studies and cancer registries. The use of an international classification system is especially important in the field of pediatric oncology, in which the low frequency of cases requires rigorous procedures to ensure data comparability. Cancer 2005. \u00a9 2005 American Cancer Society.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.20910","type":"journal-article","created":{"date-parts":[[2005,2,14]],"date-time":"2005-02-14T12:36:12Z","timestamp":1108384572000},"page":"1457-1467","source":"Crossref","is-referenced-by-count":1378,"title":["International Classification of Childhood Cancer, third edition"],"prefix":"10.1002","volume":"103","author":[{"given":"Eva","family":"Steliarova\u2010Foucher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Stiller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Lacour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kaatsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,2,14]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910400508"},{"key":"e_1_2_6_3_2","volume-title":"International Classification of Diseases for Oncology (ICD\u2010O)","author":"World Health Organization","year":"1976"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910420408"},{"key":"e_1_2_6_5_2","volume-title":"International Classification of Diseases for Oncology","author":"Percy C","year":"1992"},{"key":"e_1_2_6_6_2","volume-title":"International statistical classification of diseases and related health problems, 10th revision","author":"World Health Organization","year":"1992"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19961211)68:6<759::AID-IJC12>3.0.CO;2-W"},{"key":"e_1_2_6_8_2","series-title":"International incidence of childhood cancer","author":"Parkin DM","year":"1998"},{"key":"e_1_2_6_9_2","volume-title":"Cancer incidence and survival among children and adolescents: United States SEER Program 1975\u20131995","author":"Ries LAG","year":"1999"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(01)00005-3"},{"key":"e_1_2_6_11_2","volume-title":"International Classification of Diseases for Oncology","author":"Fritz A","year":"2000"},{"key":"e_1_2_6_12_2","volume-title":"Pathology and genetics of tumours of the nervous system. 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