{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:01:13Z","timestamp":1792144873750,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T00:00:00Z","timestamp":1119398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Although patients with cancer generally respond favorably to vaccination, they may not receive annual influenza vaccinations. The current population\u2010based study described the epidemiology and outcomes of potentially preventable, serious influenza\u2010related infections in patients with cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>From the Nationwide Inpatient Sample, the authors created a subsample that included discharges with any International Classification of Diseases, ninth revision, diagnosis code for cancer and principal diagnosis code for influenza, bronchopneumonia, or pneumonia caused by an unspecified organism. From the latter two diagnosis codes, the authors estimated excess cases during the influenza season for each year and stratum, then selected a random sample from fall and winter discharges. Subset analyses included weighted sample means, frequencies, and analysis of variance values. The authors converted charges to costs using cost\u2010to\u2010charge ratios and inflated these to 2003 U.S. dollars. Hospitalization and mortality rates were calculated using 5\u2010year cancer prevalence estimates.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The estimated mean annual hospital discharges of patients with cancer with potentially preventable, serious influenza\u2010related infections numbered 16,000. The average length and cost per stay were 6 days and &gt; $6300, respectively. Approximately 9% of patients died in the hospital and 31% needed further skilled care. The estimated age\u2010specific rates for hospitalization and death per 100,000 in the prevalent cancer population were 219 and 17.4, respectively, for patients age &lt; 65 years and 623 and 59.4, respectively, for those age \u2265 65 years. Hospitalization costs averaged $1300 more for patients age &lt; 65 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Death from influenza\u2010related infections occurred in an estimated 9% of patients with cancer hospitalized for such. Using recommended vaccination schedules for patients with cancer and their contacts reduced hospitalizations, treatment delays, and deaths in this highly susceptible population. Cancer 2005. \u00a9 2005 American Cancer Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.21203","type":"journal-article","created":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T21:11:01Z","timestamp":1119474661000},"page":"618-628","source":"Crossref","is-referenced-by-count":168,"title":["Epidemiology and outcomes of serious influenza\u2010related infections in the cancer population"],"prefix":"10.1002","volume":"104","author":[{"given":"Catherine D.","family":"Cooksley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elenir B. C.","family":"Avritscher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin N.","family":"Bekele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth V.","family":"Rolston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane M.","family":"Geraci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda S.","family":"Elting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,22]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20288"},{"key":"e_1_2_8_3_2","volume-title":"Estimate U.S. cancer prevalence counts. Who are our cancer survivors in the US? Cancer Control and Population Sciences: Research Findings","author":"National Cancer Institute","year":"2003"},{"key":"e_1_2_8_4_2","volume-title":"Cancer facts and figures 2004","author":"American Cancer Society","year":"2004"},{"key":"e_1_2_8_5_2","volume-title":"A national action plan for cancer survivorship: advancing public health strategies","author":"Center for Disease Control Division of Cancer Prevention and Control","year":"2004"},{"key":"e_1_2_8_6_2","volume-title":"Living beyond cancer: finding a new balance","author":"National Cancer Institute President's Cancer Panel","year":"2004"},{"issue":"6","key":"e_1_2_8_7_2","first-page":"1","article-title":"Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"53","author":"Harper SA","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.76.7.761"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/315320"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.11.1333"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/323085"},{"key":"e_1_2_8_12_2","volume-title":"A call to action: improving influenza and pneumoccocal immunization rates among high\u2010risk adults","author":"Poland GA","year":"1998"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.06.008"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s005200000186"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1385\/MO:19:2:71"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02098469"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-87-5-552"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200060010-00004"},{"key":"e_1_2_8_19_2","volume-title":"NIS description of data elements. Healthcare Cost and Utilization Project (HCUP) databases","author":"National Inpatient Sample (NIS)","year":"2004"},{"key":"e_1_2_8_20_2","unstructured":"Surveillance Epidemiology and End Results (SEER) Program. Seer*Stat Database. Incidence\u2010SEER 9 Regs Public\u2010Use Nov 2003 Sub (1973\u20132001).National Cancer Institute DCCPS Surveillance Research Program Cancer Statistics Branch released April 2004 based on the November 2003 submission. Available from URL:http:\/\/www.seer.cancer.gov[accessed May 31 2005]."},{"key":"e_1_2_8_21_2","volume-title":"HCUPnet","author":"Healthcare Cost and Utilization Project (HCUP)","year":"2004"},{"key":"e_1_2_8_22_2","series-title":"ICD\u20109 CM easy coder","year":"2002"},{"key":"e_1_2_8_23_2","volume-title":"United States surveillance data","author":"Centers for Disease Control","year":"1998"},{"key":"e_1_2_8_24_2","volume-title":"July 2003 Medicare cost to charge reimbursement","author":"U. S. Department of Labor Bureau of Labor Statistics","year":"2004"},{"key":"e_1_2_8_25_2","first-page":"39827","article-title":"Medicare program; changes to the hospital inpatient prospective payment systems and rates and costs of graduate medical education: fiscal year 2002 rates; provisions of the Balanced Budget Refinement Act of 1999; and provisions of the Medicare, Medicaid, and SCHIP Benefits Improvement and Protection Act of 2000. Final rules","volume":"66","author":"Centers for Medicare and HHS Medicaid Services","year":"2001","journal-title":"Federal Register."},{"key":"e_1_2_8_26_2","volume-title":"Version 11.5","author":"SPSS, Inc.","year":"2002"},{"key":"e_1_2_8_27_2","unstructured":"HouchensR ElixhauserA.Final report on calculating nationwide inpatient sample (NIS) variances. HCUP Methods Series Report #2003\u20132.Agency for Healthcare Research and Quality May 30 2003(revised March 19 2004)."},{"key":"e_1_2_8_28_2","unstructured":"AnA WattsD. New SAS procedures for analysis of sample survey data Proceedings of the Twenty\u2010Third Annual SAS Users Group International. Available from URL:http:\/\/www.ats.ucla.edu\/stat\/sas\/library\/svy_survey.pdf[accessed November 16 2004]."},{"key":"e_1_2_8_29_2","series-title":"User's guide, version 8","author":"SAS\/STAT","year":"1999"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(93)90103-8"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200001273420401"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2000.110445"},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200001273420402"},{"key":"e_1_2_8_35_2","first-page":"1286","article-title":"Update: influenza\u2010associated deaths reported among children aged <18 years\u2014United States, 2003\u201004 influenza season","volume":"52","author":"Centers for Disease Control, Prevention","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-05-1425"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.3.265"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000144662.86396.07"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcncr.21203","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.21203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T17:50:28Z","timestamp":1760291428000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.21203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6,22]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,8]]}},"alternative-id":["10.1002\/cncr.21203"],"URL":"https:\/\/doi.org\/10.1002\/cncr.21203","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6,22]]}}}