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The likelihood of a positive sentinel lymph node biopsy (SLNB) exceeds 20% for melanomas &gt;2 mm thick and approximately \u226520% of those patients with positive SLNB will be found to have residual positive lymph nodes on completion lymph node dissection. Patients with positive regional lymph nodes have an approximately \u226520% risk of regional recurrence after surgery alone, particularly if multiple lymph nodes are involved and\/or extracapsular extension is present. Postoperative adjuvant RT results in locoregional control rates of 85% to 90% or higher in high\u2010risk patients with a modest risk of complications. The impact of adjuvant RT on survival is likely minimal. Cancer 2008. \u00a9 2008 American Cancer Society.<\/jats:p>","DOI":"10.1002\/cncr.23306","type":"journal-article","created":{"date-parts":[[2008,2,7]],"date-time":"2008-02-07T18:46:18Z","timestamp":1202409978000},"page":"1189-1196","source":"Crossref","is-referenced-by-count":29,"title":["Adjuvant radiotherapy for cutaneous melanoma"],"prefix":"10.1002","volume":"112","author":[{"given":"William M.","family":"Mendenhall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Amdur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen R.","family":"Grobmyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Thomas J.","family":"George","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John 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