{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:55:35Z","timestamp":1760316935765,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2009,12,29]],"date-time":"2009-12-29T00:00:00Z","timestamp":1262044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2010,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND:<\/jats:title><jats:p>Pediatric cancer survivors who were treated before routine hepatitis C virus (HCV) screening of blood donors in 1992 have an elevated risk of transfusion\u2010acquired HCV.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p>To assess long\u2010term pediatric cancer survivors' knowledge of HCV testing and blood transfusion history, a questionnaire was administered to 9242 participants in the Childhood Cancer Survivor Study who are at risk for transfusion\u2010acquired HCV after cancer therapy from 1970 to 1986.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>More than 70% of survivors reported either no prior HCV testing (41%) or uncertainty about testing (31%), with only 29% reporting prior testing. One half recalled having a treatment\u2010related blood transfusion; those who recalled a transfusion were more likely to report HCV testing (39%) than those who did not (18%) or were unsure (20%). In multivariate models, survivors who reported no prior HCV testing were more likely to be older (odds ratio [OR] per 5\u2010year increase, 1.1; 95% confidence interval [CI], 1.0\u20101.1) and to report no care at a cancer center within the past 2 years (OR, 1.2; 95% CI, 1.0\u20101.4), no cancer treatment summary (OR, 1.3; 95% CI, 1.2\u20101.5), and no transfusions (OR, 2.6; 95% CI, 2.3\u20103.0) or uncertainty about transfusions (OR, 2.2; 95% CI, 1.9\u20102.6), and less likely to be racial\/ethnic minorities (OR, 0.9; 95% CI, 0.8\u20101.0) or survivors of acute myeloid leukemia (OR, 0.7; 95% CI, 0.5\u20101.0).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>Many pediatric cancer survivors at risk for transfusion\u2010acquired HCV are unaware of their transfusion history and prior testing for HCV and would benefit from programs to increase HCV knowledge and screening. Cancer 2010. \u00a9 2010 American Cancer Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.24810","type":"journal-article","created":{"date-parts":[[2009,12,29]],"date-time":"2009-12-29T14:34:31Z","timestamp":1262097271000},"page":"974-982","source":"Crossref","is-referenced-by-count":6,"title":["Knowledge of hepatitis C virus screening in long\u2010term pediatric cancer survivors"],"prefix":"10.1002","volume":"116","author":[{"given":"Meagan","family":"Lansdale","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Castellino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neyssa","family":"Marina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela","family":"Goodman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa M.","family":"Hudson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann C.","family":"Mertens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie M.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy","family":"Leisenring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie L.","family":"Robison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin C.","family":"Oeffinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,12,29]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"1","article-title":"Management of hepatitis C: 2002","volume":"19","year":"2002","journal-title":"NIH Consens State Sci Statements"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_2","DOI":"10.7326\/0003-4819-144-10-200605160-00004"},{"issue":"19","key":"e_1_2_6_4_2","first-page":"9","article-title":"Recommendations for prevention and control of hepatitis C virus (HCV) infection and HCV\u2010related chronic disease","volume":"47","author":"Centers for Disease Control and Prevention","year":"1998","journal-title":"MMWR Morb Mortal Wkly Rep"},{"doi-asserted-by":"publisher","key":"e_1_2_6_5_2","DOI":"10.1053\/j.gastro.2007.04.061"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_2","DOI":"10.1053\/jlts.2003.50073"},{"doi-asserted-by":"publisher","key":"e_1_2_6_7_2","DOI":"10.1002\/hep.22165"},{"doi-asserted-by":"publisher","key":"e_1_2_6_8_2","DOI":"10.2105\/AJPH.90.10.1562"},{"doi-asserted-by":"publisher","key":"e_1_2_6_9_2","DOI":"10.1016\/S0002-9343(99)00373-3"},{"doi-asserted-by":"publisher","key":"e_1_2_6_10_2","DOI":"10.1182\/blood-2003-07-2565"},{"doi-asserted-by":"publisher","key":"e_1_2_6_11_2","DOI":"10.1182\/blood.V90.3.1315.1315_1315_1320"},{"doi-asserted-by":"publisher","key":"e_1_2_6_12_2","DOI":"10.1007\/BF01955056"},{"doi-asserted-by":"publisher","key":"e_1_2_6_13_2","DOI":"10.1097\/00043426-200303000-00002"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"3672","DOI":"10.1182\/blood.V93.11.3672.411k04_3672_3677","article-title":"Chronic hepatitis C virus infections in leukemia survivors: prevalence, viral load, and severity of liver disease","volume":"93","author":"Paul IM","year":"1999","journal-title":"Blood"},{"doi-asserted-by":"publisher","key":"e_1_2_6_15_2","DOI":"10.1097\/00043426-200111000-00012"},{"key":"e_1_2_6_16_2","doi-asserted-by":"crossref","first-page":"3065","DOI":"10.1182\/blood.V95.10.3065","article-title":"Hepatitis C infection among survivors of childhood cancer","volume":"95","author":"Strickland DK","year":"2000","journal-title":"Blood"},{"unstructured":"Children's Oncology Group Long\u2010Term Follow\u2010Up Guidelines for Survivors of Childhood Adolescent and Young Adult Cancer. 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