{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T16:44:48Z","timestamp":1760287488789,"version":"build-2065373602"},"reference-count":47,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2010,5,28]],"date-time":"2010-05-28T00:00:00Z","timestamp":1275004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND:<\/jats:title><jats:p>Hispanics have a greater risk of early treatment failure after hematopoietic stem cell transplantation (HCT) compared with non\u2010Hispanic whites. However, long\u2010term morbidity among Hispanics has not been described.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p>Health\u2010related outcomes were examined in 159 Hispanic patients and 825 non\u2010Hispanic white patients who underwent HCT between 1974 and 1998 and survived a mean of 8.7 years. Patients completed a detailed questionnaire about sociodemographic factors and the occurrence of chronic health conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>Exposure to total body irradiation (TBI) (odds ratio [OR], 1.94; 95% confidence interval [CI], 1.06\u20103.56; <jats:italic>P<\/jats:italic> = .03), the presence of chronic graft versus host disease (GvHD) (OR, 3.99; 95% CI, 1.94\u20108.24; <jats:italic>P<\/jats:italic> = .002), and health insurance coverage (OR, 3.46; 95% CI, 1.5\u20108.01; <jats:italic>P<\/jats:italic> = .004), were associated significantly with severe\/life\u2010threatening conditions. Compared with non\u2010Hispanic white patients, Hispanic patients were 53% less likely to report severe\/life\u2010threatening conditions (OR, 0.47; 95% CI, 0.27\u20100.83; <jats:italic>P<\/jats:italic> = .009) after adjusting for relevant clinical variables. This effect size was mitigated (OR, 0.56; 95%CI, 0.29\u20101.08; <jats:italic>P<\/jats:italic> = .08) after adjusting for health insurance coverage.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>Hispanics were less likely to report severe\/life\u2010threatening health conditions after HCT than non\u2010Hispanic whites\u2014a difference that decreased in magnitude and significance after taking health insurance into consideration. Although the current results confirmed the role of TBI and chronic GvHD, in the current study, the role of a lack of health insurance coverage was identified as a mediator of the lower prevalence of self\u2010reported long\u2010term morbidity in Hispanics. Cancer 2010. \u00a9 2010 American Cancer Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.25157","type":"journal-article","created":{"date-parts":[[2010,5,28]],"date-time":"2010-05-28T12:58:46Z","timestamp":1275051526000},"page":"4152-4159","source":"Crossref","is-referenced-by-count":3,"title":["Ethnic differences in chronic health conditions after hematopoietic cell transplantation"],"prefix":"10.1002","volume":"116","author":[{"given":"Saro H.","family":"Armenian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Can\u2010Lan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer Berano","family":"Teh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mukta","family":"Arora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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