{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:53:52Z","timestamp":1791230032161,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2012,1,3]],"date-time":"2012-01-03T00:00:00Z","timestamp":1325548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND:<\/jats:title><jats:p>Primary tumors of the spinal cord, spinal meninges, and cauda equina are relatively rare, and a paucity of population\u2010based data exist on tumors in these sites. This study intends to augment the current literature by examining incidence of these tumors on a national level.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p>Data from central cancer registries in the National Program of Cancer Registries (NPCR) and Surveillance, Epidemiology, and End Results (SEER) programs for 2004\u20102007 (covering 99.2% of US population) and 1999\u20102007 (covering 89.4% of US population) were analyzed. Analyses for diagnosis years 2004\u20102007 included cases of malignant and nonmalignant primary spinal cord, spinal meninges, and cauda equina tumors. Descriptive statistics including estimated age\u2010adjusted incidence rates standardized to the 2000 US standard population were conducted for both malignant and nonmalignant primary spinal tumors from cases diagnosed during 2004\u20102007 as well as trend analyses on malignant cases of primary spinal tumors (n = 5103) for cases diagnosed during 1999\u20102007 using SEER*Stat 6.6.2 software.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>There were 2576 cases of malignant primary spinal tumors and 9136 cases of nonmalignant primary spinal tumors in 2004\u20102007. The incidence of malignant and nonmalignant primary spinal tumors combined differed by age, sex, race, and ethnicity. Results of trend analyses indicated that malignant primary spinal tumors have been stable throughout the 1999\u20102007 period.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>This large population\u2010based study adds new insights into the descriptive epidemiology of primary spinal cord, spinal meninges, and cauda equina tumors by providing in\u2010depth analyses of the incidence of these tumors on a national level. Cancer 2012. \u00a9 2012 American Cancer Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.27390","type":"journal-article","created":{"date-parts":[[2012,1,4]],"date-time":"2012-01-04T20:35:09Z","timestamp":1325709309000},"page":"4220-4227","source":"Crossref","is-referenced-by-count":209,"title":["Descriptive epidemiology of malignant and nonmalignant primary spinal cord, spinal meninges, and cauda equina tumors, United States, 2004\u20102007"],"prefix":"10.1002","volume":"118","author":[{"given":"Linh M.","family":"Duong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridget J.","family":"McCarthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger E.","family":"McLendon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therese A.","family":"Dolecek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Kruchko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynda L.","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umed A.","family":"Ajani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,3]]},"reference":[{"key":"e_1_2_8_2_2","volume-title":"CBTRUS Statistical Report: Primary Brain Tumors in the United States, 1998\u20102002","author":"Central Brain Tumor Registry of the United States","year":"2005"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.1989.4.2.77"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000075953"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.3171\/2010.3.SPINE09430"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000026269"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-007-9507-z"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/1.3.205"},{"key":"e_1_2_8_9_2","unstructured":"Centers for Disease Control and Prevention (CDC) Division of Cancer Prevention and Control (DCPC) Cancer Surveillance Branch (CSB) National Program of Cancer Registries (NPCR). About the Program. Available at:http:\/\/www.cdc.gov\/cancer\/npcr\/about.htmAccessed January 14 2011."},{"key":"e_1_2_8_10_2","volume-title":"2009\u20102010 CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in Eighteen States in 2002\u20102006","author":"Central Brain Tumor Registry of the United States","year":"2009"},{"key":"e_1_2_8_11_2","volume-title":"Public Law 107\u2010260. Benign Brain Tumor Cancer Registries Amendment Act. Diseases. Health and Health Care","author":"Senate and House of Representatives of the United States","year":"2002"},{"key":"e_1_2_8_12_2","unstructured":"Centers for Disease Control and Prevention Division of Cancer Prevention and Control Cancer Surveillance Branch National Program of Cancer Registries. United States Cancer Statistics Publication Standards. Available at: (http:\/\/www.cdc.gov\/cancer\/npcr\/uscs\/2005\/technical_notes\/criteria.htmAccessed January 14 2011."},{"key":"e_1_2_8_13_2","volume-title":"International Classification of Diseases for Oncology","year":"1990"},{"key":"e_1_2_8_14_2","volume-title":"International Classification of Diseases for oncology","year":"2000"},{"key":"e_1_2_8_15_2","volume-title":"CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2004\u20102007","author":"Central Brain Tumor Registry of the United States","year":"2011"},{"key":"e_1_2_8_16_2","volume-title":"World Health Organization Classification of Tumours of the Central Nervous System","author":"Louis DN","year":"2007"},{"key":"e_1_2_8_17_2","unstructured":"Surveillance Research Program. National Cancer Institute SEER*Stat software version 6.6.2. Available at:www.seer.cancer.gov\/seerstat"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1159\/000075952"},{"key":"e_1_2_8_19_2","first-page":"206","article-title":"Epidemiology of central nervous system tumors in Labin area, Croatia, 1974\u20102001","volume":"45","author":"Materljan E","year":"2004","journal-title":"Croat Med J."},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1159\/000110757"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1958.15.6.0627"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/3.3.152"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcncr.27390","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.27390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T15:50:05Z","timestamp":1760284205000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.27390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,3]]},"references-count":21,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["10.1002\/cncr.27390"],"URL":"https:\/\/doi.org\/10.1002\/cncr.27390","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,3]]}}}