{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:28:55Z","timestamp":1789424935222,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T00:00:00Z","timestamp":1365552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Current treatments for lymphedema after breast cancer treatment are expensive and require ongoing intervention. Clinical experience and our preliminary published results suggest that acupuncture is safe and potentially useful. This study evaluates the safety and potential efficacy of acupuncture on upper\u2010limb circumference in women with lymphedema.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Women with a clinical diagnosis of breast cancer\u2212related lymphedema (BCRL) for 0.5\u20105 years and with affected arm circumference \u22652 cm larger than unaffected arm received acupuncture treatment twice weekly for 4 weeks. Affected and unaffected arm circumferences were measured before and after each acupuncture treatment. Response, defined as \u226530% reduction in circumference difference between affected\/unaffected arms, was assessed. Monthly follow\u2010up calls for 6 months thereafter were made to document any complications and self\u2010reported lymphedema status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Among 37 enrolled patients, 33 were evaluated; 4 discontinued due to time constraints. Mean reduction in arm circumference difference was 0.90 cm (95% CI, 0.72\u20101.07;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.0005). Eleven patients (33%) exhibited a reduction of \u226530% after acupuncture treatment. Seventy\u2010six percent of patients received all treatments; 21% missed 1 treatment, and another patient missed 2 treatments. During the treatment period, 14 of the 33 patients reported minor complaints, including mild local bruising or pain\/tingling. There were no serious adverse events and no infections or severe exacerbations after 255 treatment sessions and 6 months of follow\u2010up interviews.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>\n                      Acupuncture for BCRL appears safe and may reduce arm circumference. Although these results await confirmation in a randomized trial, acupuncture can be considered for women with no other options for sustained arm circumference reduction.\n                      <jats:bold>\n                        <jats:italic>Cancer<\/jats:italic>\n                        2013;119:2455\u20102461\n                      <\/jats:bold>\n                      . \u00a9\n                      <jats:italic>2013 American Cancer Society<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.28093","type":"journal-article","created":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T11:52:54Z","timestamp":1365594774000},"page":"2455-2461","source":"Crossref","is-referenced-by-count":56,"title":["Acupuncture in the treatment of upper\u2010limb lymphedema"],"prefix":"10.1002","volume":"119","author":[{"given":"Barrie R.","family":"Cassileth","sequence":"first","affiliation":[{"name":"Integrative Medicine Service Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly J.","family":"Van Zee","sequence":"additional","affiliation":[{"name":"Department of Surgery Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Simon","family":"Yeung","sequence":"additional","affiliation":[{"name":"Integrative Medicine Service Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marci I.","family":"Coleton","sequence":"additional","affiliation":[{"name":"Integrative Medicine Service Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Cohen","sequence":"additional","affiliation":[{"name":"Breast Cancer Medicine Service Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi H.","family":"Chan","sequence":"additional","affiliation":[{"name":"Integrative Medicine Service Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Vickers","sequence":"additional","affiliation":[{"name":"Integrative Medicine Service and Department of Epidemiology and Biostatistics Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel D.","family":"Sjoberg","sequence":"additional","affiliation":[{"name":"Integrative Medicine Service and Department of Epidemiology and Biostatistics Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clifford A.","family":"Hudis","sequence":"additional","affiliation":[{"name":"Breast Cancer Medicine Service Memorial Sloan\u2010Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2006.04.022"},{"key":"e_1_2_7_3_1","unstructured":"American Cancer Society.Breast Cancer Facts & Figures2011\u20102012.http:\/\/www.cancer.org\/Research\/CancerFactsFigures\/BreastCancerFactsFigures\/breast\u2010cancer\u2010facts\u2010and\u2010figures\u20102011\u20102012. 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