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The HT\u20101 cells expressed CD1, CD2, CD3, CD4, CD5, CD7, CD8, CD57, and terminal deoxynucleotidyl transferase (TdT) but lacked B\u2010cell\u2010associated antigens and myeloid\u2010associated antigens. In addition, HT\u20101 cells had rearranged T\u2010cell receptor (TCR) \u03b2\u2010chain gene and \u03b3\u2010chain gene but retained germlines of immunoglobulin (Ig) heavy chain gene. These findings indicate that HT\u20101 cell line represents a common thymocyte in the T\u2010cell lineage. Cytogenetic studies revealed that HT\u20101 cells carry an inversion (inv) of the long arm of chromosome 14. This cell line is the second T\u2010cell line carrying inv(14) chromosome and may be useful for the molecular investigation of the cytogenetic break points of inv(14).<\/jats:p>","DOI":"10.1002\/cncr.2820690527","type":"journal-article","created":{"date-parts":[[2010,8,15]],"date-time":"2010-08-15T15:08:20Z","timestamp":1281884900000},"page":"1235-1240","source":"Crossref","is-referenced-by-count":9,"title":["Establishment and characterization of a human T\u2010cell lymphoblastic lymphoma ceil line (HT\u20101) carrying an inversion of chromosome 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