{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:42:52Z","timestamp":1791826972046,"version":"4.3.4"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,11,11]],"date-time":"2013-11-11T00:00:00Z","timestamp":1384128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Young women may experience delays in diagnosis of breast cancer, and these delays may contribute to poorer outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>In a prospective, multicenter cohort study, women recently diagnosed with breast cancer at age \u226440 years were surveyed regarding their initial signs or symptoms of cancer and delays in diagnosis. Self delay was defined as \u226590 days between the first sign or symptom and a patient's first visit to consult a health care provider. Care delay was defined as \u226590 days between that first visit and the diagnosis of breast cancer. In a medical record review, tumor characteristics were assessed, including disease stage. Univariate and multivariate models were used to assess for predictors of self delay, care delay, and advanced stage in the self\u2010detected subset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      In 585 eligible participants, the first sign or symptom of cancer was a self\u2010detected breast abnormality for 80%, a clinical breast examination abnormality for 6%, an imaging abnormality for 12%, and a systemic symptom for 1%. Among women with self\u2010detected cancers, 17% reported a self delay, and 12% reported a care delay. Self delays were associated with poorer financial status (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.01). Among young women with self\u2010detected breast cancers, care delay was associated at trend level (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.06) with higher stage in multivariate modeling.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>\n                      Most young women detect their own breast cancers, and most do not experience long delays before diagnosis. Women with fewer financial resources are more likely to delay seeking medical attention for a self\u2010detected breast abnormality.\n                      <jats:bold>\n                        <jats:italic>Cancer<\/jats:italic>\n                        2014;120:20\u201325\n                      <\/jats:bold>\n                      . \u00a9\n                      <jats:italic>2013 American Cancer Society<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.28287","type":"journal-article","created":{"date-parts":[[2013,11,11]],"date-time":"2013-11-11T09:20:45Z","timestamp":1384161645000},"page":"20-25","source":"Crossref","is-referenced-by-count":115,"title":["Breast cancer presentation and diagnostic delays in young women"],"prefix":"10.1002","volume":"120","author":[{"given":"Kathryn J.","family":"Ruddy","sequence":"first","affiliation":[{"name":"Dana\u2010Farber Cancer Institute Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shari","family":"Gelber","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rulla M.","family":"Tamimi","sequence":"additional","affiliation":[{"name":"Channing Division of Network Medicine Brigham and Women's Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Schapira","sequence":"additional","affiliation":[{"name":"Medical Oncology Massachusetts General Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven E.","family":"Come","sequence":"additional","affiliation":[{"name":"Medical Oncology Beth Israel Deaconess Medical Center Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan E.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric P.","family":"Winer","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann H.","family":"Partridge","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,11]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Breast Cancer Facts and Figures 2007\u20132008","author":"American Cancer Society","year":"2007"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2006.03.055"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.10.3754"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602623"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2011-0469"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)02143-1"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:BREA.0000032980.55245.c3"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-011-1872-9"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20073"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2004.02.012"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27581"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr3156"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdf039"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdl145"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcncr.28287","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.28287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T17:02:54Z","timestamp":1760288574000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.28287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,11]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1002\/cncr.28287"],"URL":"https:\/\/doi.org\/10.1002\/cncr.28287","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,11]]}}}