{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T07:26:12Z","timestamp":1787901972818,"version":"build-2784847793"},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,11,4]],"date-time":"2014-11-04T00:00:00Z","timestamp":1415059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Research on health\u2010related quality of life (HRQOL) among older adult cancer survivors is mostly confined to breast cancer, prostate cancer, colorectal cancer, and lung cancer, which account for 63% of all prevalent cancers. Much less is known about HRQOL in the context of less common cancer sites.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>HRQOL was examined with the 36\u2010Item Short Form Health Survey, version 1, and the Veterans RAND 12\u2010Item Health Survey in patients with selected cancers (kidney cancer, bladder cancer, pancreatic cancer, upper gastrointestinal cancer, cancer of the oral cavity and pharynx, uterine cancer, cervical cancer, thyroid cancer, melanoma, chronic leukemia, non\u2010Hodgkin lymphoma, and multiple myeloma) and in individuals without cancer on the basis of data linked from the Surveillance, Epidemiology, and End Results cancer registry system and the Medicare Health Outcomes Survey. Scale scores, Physical Component Summary (PCS) and Mental Component Summary (MCS) scores, and a utility metric (Short Form 6D\/Veterans RAND 6D), adjusted for sociodemographic characteristics and other chronic conditions, were calculated. A 3\u2010point difference in the scale scores and a 2\u2010point difference in the PCS and MCS scores were considered to be minimally important differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Data from 16,095 cancer survivors and 1,224,549 individuals without a history of cancer were included. The results indicated noteworthy deficits in physical health status. Mental health was comparable, although scores for the Role\u2013Emotional and Social Functioning scales were worse for patients with most types of cancer versus those without cancer. Survivors of multiple myeloma and pancreatic malignancies reported the lowest scores, with their PCS\/MCS scores less than those of individuals without cancer by 3 or more points.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>\n                      HRQOL surveillance efforts revealed poor health outcomes among many older adults and specifically among survivors of multiple myeloma and pancreatic cancer.\n                      <jats:bold>\n                        <jats:italic>Cancer<\/jats:italic>\n                        2015;121:758\u2013765.\n                      <\/jats:bold>\n                      \u00a9\n                      <jats:italic>2014 American Cancer Society<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.29119","type":"journal-article","created":{"date-parts":[[2014,11,4]],"date-time":"2014-11-04T10:38:00Z","timestamp":1415097480000},"page":"758-765","source":"Crossref","is-referenced-by-count":153,"title":["Health\u2010related quality of life in older adult survivors of selected cancers: Data from the\n                    <scp>SEER<\/scp>\n                    \u2010\n                    <scp>MHOS<\/scp>\n                    linkage"],"prefix":"10.1002","volume":"121","author":[{"given":"Erin E.","family":"Kent","sequence":"first","affiliation":[{"name":"Applied Research Program, National Cancer Institute Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Ambs","sequence":"additional","affiliation":[{"name":"Applied Research Program, National Cancer Institute Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra A.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Applied Research Program, National Cancer Institute Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven B.","family":"Clauser","sequence":"additional","affiliation":[{"name":"Applied Research Program, National Cancer Institute Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley Wilder","family":"Smith","sequence":"additional","affiliation":[{"name":"Applied Research Program, National Cancer Institute Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron D.","family":"Hays","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Health Services Research University of California Los Angeles Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0b013e3181b9c5b9"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1586\/erp.10.15"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.4929"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2007.06.001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-9966-27-32"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.572"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3816\/CCC.2007.n.039"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2008.02.018"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1586\/erp.10.81"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.07.036"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-11-0729"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)70471-X"},{"key":"e_1_2_7_14_1","first-page":"1","article-title":"SEER\u2010MHOS: a new federal collaboration on cancer outcomes research","volume":"29","author":"Clauser SB","year":"2008","journal-title":"Health Care Financ Rev"},{"key":"e_1_2_7_15_1","first-page":"5","article-title":"Overview of the SEER\u2013Medicare Health Outcomes Survey linked dataset","volume":"29","author":"Ambs A","year":"2008","journal-title":"Health Care Financ Rev"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-90-481-9485-8_17"},{"key":"e_1_2_7_17_1","first-page":"473","article-title":"The MOS 36\u2010Item Short\u2010Form Health Survey (SF\u201036)","volume":"30","author":"Ware JE","year":"1992","journal-title":"I. 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