{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T07:57:03Z","timestamp":1769327823418,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"15","license":[{"start":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T00:00:00Z","timestamp":1429056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"CCO CHair in Population and THerapeutics"},{"name":"PMH Foundation - ALan Brown Chair in Molecular Genomics"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Second\u2010hand smoke (SHS) is a significant barrier to smoking cessation after a diagnosis of cancer in patients with lung as well as head and neck cancers. In the current study, the authors evaluated the effect of SHS on smoking cessation among patients with those cancers not traditionally perceived to be strongly associated with smoking.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Patients recruited from a single tertiary care center completed a self\u2010administered questionnaire. Multivariate logistic regression and Cox proportional hazards models evaluated the association of sociodemographics, clinicopathological variables, and exposure to SHS with either smoking cessation or time to quitting.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>In all, 926 patients with diverse cancer subtypes completed the questionnaire. Of the 161 who were current smokers at the time of their cancer diagnosis, 48% quit after diagnosis. Lack of exposure to SHS at home was found to be associated with smoking cessation at any time after diagnosis (adjusted odd ratio, 4.28; 95% confidence interval, 1.56\u201011.78 [<jats:italic>P =<\/jats:italic>.005]), with similar trends noted 1 year after diagnosis (adjusted odds ratio, 2.56; 95% confidence interval, 0.91\u20107.22 [<jats:italic>P =<\/jats:italic>.08]). There was a significant inverse dose\u2010response relationship between hours of SHS exposure at home and smoking cessation. Spousal and peer smoking were not found to be significantly associated with smoking cessation on multivariate analysis (<jats:italic>P<\/jats:italic>&gt;.05). Kaplan\u2010Meier analysis found that of patients who did quit smoking, 61% quit within 6 months of their cancer diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Exposure to SHS at home is a significant barrier to smoking cessation in patients whose cancers are not traditionally perceived as being related to tobacco. SHS should be a key consideration in the development of survivorship programs geared toward smoking cessation for all patients with cancer. <jats:bold><jats:italic>Cancer<\/jats:italic> 2015;121:2655\u20132663<\/jats:bold>. \u00a9 <jats:italic>2015 American Cancer Society<\/jats:italic>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.29340","type":"journal-article","created":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T13:21:34Z","timestamp":1429104094000},"page":"2655-2663","source":"Crossref","is-referenced-by-count":21,"title":["The role of second\u2010hand smoke exposure on smoking cessation in non\u2013tobacco\u2010related cancers"],"prefix":"10.1002","volume":"121","author":[{"given":"Lawson","family":"Eng","sequence":"first","affiliation":[{"name":"Division of Medical Oncology and Hematology Department of Medicine Princess Margaret Cancer Centre\/University Health Network and University of Toronto Toronto Ontario Canada"},{"name":"Ontario Cancer Institute Toronto Ontario Canada"},{"name":"Department of Medicine University Health Network Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Princess Margaret Cancer Centre\/University Health Network and University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Princess Margaret Cancer Centre\/University Health Network and University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Pringle","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chongya","family":"Niu","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology and Hematology Department of Medicine Princess Margaret Cancer Centre\/University Health Network and University of Toronto Toronto Ontario Canada"},{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Mahler","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Charow","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodie","family":"Villeneuve","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oleksandr","family":"Halytskyy","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Lam","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoko","family":"Tiessen","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Catherine","family":"Brown","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris","family":"Howell","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology and Hematology Department of Medicine Princess Margaret Cancer Centre\/University Health Network and University of Toronto Toronto Ontario Canada"},{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meredith E.","family":"Giuliani","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"},{"name":"Department of Radiation Oncology Princess Margaret Cancer Centre Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer M.","family":"Jones","sequence":"additional","affiliation":[{"name":"Ontario Cancer Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shabbir M. 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