{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:01:53Z","timestamp":1777518113481,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2015,5,18]],"date-time":"2015-05-18T00:00:00Z","timestamp":1431907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["CA148576"],"award-info":[{"award-number":["CA148576"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"name":"HMO Research Network Virtual Data Warehouse","award":["U19CA79689"],"award-info":[{"award-number":["U19CA79689"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Cervical cancer screening and follow\u2010up guidelines have changed considerably in recent years, but to the authors' knowledge few published reports exist to estimate the impact of these changes in community\u2010based settings. The authors examined the patterns and results of cervical cancer testing and follow\u2010up over a decade in 4 geographically diverse US health care systems to inform the future evaluation of changes resulting from increased uptake of the human papillomavirus (HPV) vaccination.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>The authors studied women aged 21 to 65 years who were members of one of these health systems at any time between 1998 and 2007. Data were collected and standardized across sites, based on receipt of Papanicolaou (Pap) and HPV tests, HPV vaccination, cervical biopsies, and treatment of cervical dysplasia. Annual rates (per 1000 person\u2010years) of Pap testing, HPV testing, and cervical biopsy and treatment procedures were calculated. Screening intervals and trends in the results of screening Pap tests and cervical biopsies also were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Pap testing rates decreased (from 483 per 1000 person\u2010years in 2000 to 412 per 1000 person\u2010years in 2007) and HPV testing rates increased over the study period. Screening frequency varied across health care systems, and many women continued to receive annual testing. All 4 sites moved to less frequent screening over the study period without marked changes in the overall use of cervical biopsy or treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Despite differences over time and across health plans in rates of cervical cancer testing and follow\u2010up cervical procedures, the authors found no notable differences in Pap test results, diagnostic or treatment procedure rates, or pathological outcomes. This finding suggests that the longer screening intervals did not lead to more procedures or more cancer diagnoses. <jats:bold><jats:italic>Cancer<\/jats:italic> 2015;121:2976\u20132983.<\/jats:bold> \u00a9 <jats:italic>2015 American Cancer Society<\/jats:italic>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.29445","type":"journal-article","created":{"date-parts":[[2015,5,18]],"date-time":"2015-05-18T19:08:05Z","timestamp":1431976085000},"page":"2976-2983","source":"Crossref","is-referenced-by-count":9,"title":["Cervical cancer screening and follow\u2010up in 4 geographically diverse <scp>US<\/scp> health care systems, 1998 through 2007"],"prefix":"10.1002","volume":"121","author":[{"given":"Sheila","family":"Weinmann","sequence":"first","affiliation":[{"name":"The Center for Health Research Kaiser Permanente Northwest Portland Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew E.","family":"Williams","sequence":"additional","affiliation":[{"name":"Maine Medical Center Research Institute Portland Maine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aruna","family":"Kamineni","sequence":"additional","affiliation":[{"name":"Group Health Research Institute Seattle Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana S.M.","family":"Buist","sequence":"additional","affiliation":[{"name":"Group Health Research Institute Seattle Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin E.","family":"Masterson","sequence":"additional","affiliation":[{"name":"The Center for Health Research Kaiser Permanente Northwest Portland Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha K.","family":"Stout","sequence":"additional","affiliation":[{"name":"Department of Population Medicine Harvard Medical School Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azadeh","family":"Stark","sequence":"additional","affiliation":[{"name":"Geisinger Center for Health Research Danville Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyler R.","family":"Ross","sequence":"additional","affiliation":[{"name":"Group Health Research Institute Seattle Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Owens","sequence":"additional","affiliation":[{"name":"Meyers Primary Care Institute University of Massachusetts Medical School Fallon Community Health Plan Reliant Medical Group Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terry S.","family":"Field","sequence":"additional","affiliation":[{"name":"Meyers Primary Care Institute University of Massachusetts Medical School Fallon Community Health Plan Reliant Medical Group Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chyke A.","family":"Doubeni","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,18]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"714","article-title":"Effect of cervical cancer screening in Scandinavia","volume":"63","author":"Day NE","year":"1984","journal-title":"Obstet 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