{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T03:49:24Z","timestamp":1793245764292,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T00:00:00Z","timestamp":1464048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NIH\/NCI Cancer Center","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>The purpose of this study was to investigate the utility and clinical impact of second\u2010opinion interpretations of outside neuroimaging studies by oncologic neuroradiologists at a National Cancer Institute\u2013designated cancer center.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>We performed a retrospective analysis of initial outside and second\u2010opinion radiology reports from 300 computed tomography and magnetic resonance imaging studies and identified cases with discrepancies between the two reports. An adult neuro\u2010oncologist, pediatric neuro\u2010oncologist, and head and neck surgeon reviewed each pair of discrepant reports based on their area of expertise, patient age, and the type of study performed. The clinicians were blinded to the origin of each report and recorded whether the differences in the reports would have led to a change in patient management and\/or disease staging. Histopathologic analysis, clinical assessment, and\/or minimum 3\u2010month imaging follow\u2010up served as the reference standards to establish which of the 2 reports was correct.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Among the 283 cases that met our study criteria, there were 55 neuroimaging studies with disagreements (19%) between the initial outside report and second\u2010opinion interpretation. Patient management and\/or disease stage would have been altered in 42 of 283 cases (15%) based on report differences as determined by the 2 neuro\u2010oncologists and the surgeon participating in the study. Sufficient follow\u2010up was available in 35 of 42 cases (83%). The second\u2010opinion interpretation was correct 100% of the time (35\/35).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Second\u2010opinion interpretations of neuroimaging studies by subspecialized oncologic neuroradiologists provide added value by reducing error and optimizing the care of cancer patients. <jats:bold><jats:italic>Cancer<\/jats:italic> 2016<\/jats:bold>. \u00a9 <jats:italic>2016 American Cancer Society<\/jats:italic>. <jats:italic><jats:bold>Cancer 2016;122:2708\u20132714.<\/jats:bold> \u00a9 2016 American Cancer Society.<\/jats:italic><\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.30083","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T23:19:09Z","timestamp":1464131949000},"page":"2708-2714","source":"Crossref","is-referenced-by-count":52,"title":["Second\u2010opinion interpretations of neuroimaging studies by oncologic neuroradiologists can help reduce errors in cancer care"],"prefix":"10.1002","volume":"122","author":[{"given":"Vaios","family":"Hatzoglou","sequence":"first","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center New York New York"},{"name":"Brain Tumor Center Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio M.","family":"Omuro","sequence":"additional","affiliation":[{"name":"Department of Neurology Memorial Sloan Kettering Cancer Center New York New York"},{"name":"Brain Tumor Center Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Haque","sequence":"additional","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Khakoo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Ganly","sequence":"additional","affiliation":[{"name":"Department of Surgery Head and Neck Service, Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Hun","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Medical Physics Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amita","family":"Shukla\u2010Dave","sequence":"additional","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center New York New York"},{"name":"Department of Medical Physics Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Fatovic","sequence":"additional","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Gaal","sequence":"additional","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei I.","family":"Holodny","sequence":"additional","affiliation":[{"name":"Department of Radiology Memorial Sloan Kettering Cancer Center New York New York"},{"name":"Brain Tumor Center Memorial Sloan Kettering Cancer Center New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,24]]},"reference":[{"issue":"5","key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"745","DOI":"10.6004\/jnccn.2014.0182","article-title":"The Affordable Care Act: where are we now? 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